866579-96-6

Basic information

• Product Name: 2'-Fluoro-4'-nitroacetophenone
• Synonyms: 2'-Fluoro-4'-nitroacetophenone;1-(2-fluoro-4-nitrophenyl)-Ethanone
• CAS NO: 866579-96-6
• Molecular Formula: C₈H₆FNO₃
• Molecular Weight: 183.1365432
• Mol File: 866579-96-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-Fluoro-4'-nitroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-Fluoro-4'-nitroacetophenone(866579-96-6)
• EPA Substance Registry System: 2'-Fluoro-4'-nitroacetophenone(866579-96-6)

Safety Data

• Hazardous Substances Data: 866579-96-6(Hazardous Substances Data)

Usage

Description

2'-Fluoro-4'-nitroacetophenone is a chemical compound characterized by the molecular formula C8H6FNO3. It is a yellow solid with a molecular weight of 181.13 g/mol. 2'-Fluoro-4'-nitroacetophenone is known for its versatile chemical properties and potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
2'-Fluoro-4'-nitroacetophenone is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2'-Fluoro-4'-nitroacetophenone serves as an intermediate for the production of different agrochemicals. Its role in this industry is crucial for the development of effective and innovative products for agricultural applications.
Used in Organic Compounds Synthesis:
2'-Fluoro-4'-nitroacetophenone is also used as an intermediate in the synthesis of other organic compounds. Its presence in these reactions contributes to the creation of a wide range of chemical products with diverse applications.
Used in Research and Development:
2'-Fluoro-4'-nitroacetophenone is commonly used in research and development settings, particularly within the pharmaceutical industry. Its versatile chemical properties make it an essential tool for scientists and researchers working on new discoveries and advancements in various fields.
It is important to handle 2'-Fluoro-4'-nitroacetophenone with caution, as it may be hazardous if not properly managed and stored.

Upstream product

• 403-23-6 2-fluoro-4-nitrobenzoyl chloride 
• 108-59-8 malonic acid dimethyl ester 
• 100-19-6 (4-nitrophenyl)ethanone 
• 25115-58-6 1-(4-nitrophenyl)ethan-1-one O-methyl oxime 

Downstream Products

• 607713-48-4 5-(4-amino-2-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine 
• 1239719-71-1 C₁₀H₇FN₂O₃ 
• 403-24-7 2-fluoro-4-nitrobenzoic acid 
• 112279-56-8 1-(4-amino-2-fluorophenyl)ethanone 

Relevant articles and documents

Synthesis of 2-fluorocholine aryl carbonyl compounds

The invention provides a method for synthesizing 2-fluoroarylcarbonyl compounds, which comprises the following steps: converting arylcarbonyl compounds into corresponding carbonyl oxime ether compounds, mildly implementing aryl hydrocarbon chain direct fluoridation of high-selectivity oximido substituent group ortho-position in the presence of a palladium catalyst, a fluoridation reagent and additives, and finally, rehydrolyzing oxime ethers under the action of acid to obtain the 2-fluoroarylcarbonyl compounds. The fluoridation method has the advantages of mild reaction conditions, high substrate adaptability, high fluoridation selectivity and the like, is simple to operate, and has higher application research value.