867022-57-9 Usage
General Description
L-Valine, N-[(4-bromophenyl)methyl]-N-(1-oxopentyl)- is a compound that belongs to the family of organic compounds called alpha amino acids. It is a non-essential amino acid, which means it can be synthesized by the body and is not required to be obtained through dietary sources. L-Valine is an essential component of proteins and is involved in various biological processes, including the synthesis of muscle tissue and the maintenance of nitrogen balance in the body. The specific chemical structure N-[(4-bromophenyl)methyl]-N-(1-oxopentyl)- indicates that it contains a valine molecule with additional chemical groups attached to it, which may alter its properties and potential applications in biochemical and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 867022-57-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,7,0,2 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 867022-57:
(8*8)+(7*6)+(6*7)+(5*0)+(4*2)+(3*2)+(2*5)+(1*7)=179
179 % 10 = 9
So 867022-57-9 is a valid CAS Registry Number.
867022-57-9Relevant articles and documents
A process for the preparation of angiotensin II antagonistic compounds
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Page/Page column 6-7, (2008/06/13)
A process for the preparation of angiotensin II antagonists and novel intermediates useful for the synthesis thereof.
PROCESS FOR OBTAINING VALINE DERIVATIVES USEFUL FOR OBTAINING A PHARMACEUTICALLY ACTIVE COMPOUND
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Page/Page column 18, (2008/06/13)
The invention provides a method for obtaining the intermediate (II), useful for manufacturing Valsartan and a drug directed to a treatment of arterial hypertension or heart failure. The process comprises a) Imination of the aldehyde group of a compound (VII) by L-Valine (IV) salts with organic or inorganic bases and a polar solvent or water, where X means halogen or an-OSO2R group, where R is CF3, tolyl, methyl or F; to give an imine-type compound (VIII), where B+ is the protonated form of an organic base or an alkaline cation; b) Reduction of the imine group of the compound (VIII) followed by acidification, to give the compound (VI); and c) N-Acylation of the compound (VI) with valeryl chloride to give the compound (II). Steps a) and b) can be performed in a "one pot" reaction.
