867150-27-4

Basic information

• Product Name: (4R,6S)-{6-([4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl]oxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid ethyl ester
• Synonyms: (4R,6S)-{6-([4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl]oxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid ethyl ester
• CAS NO: 867150-27-4
• Molecular Weight: 533.984
• Mol File: 867150-27-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,6S)-{6-([4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl]oxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,6S)-{6-([4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl]oxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid ethyl ester(867150-27-4)
• EPA Substance Registry System: (4R,6S)-{6-([4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl]oxymethyl)-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid ethyl ester(867150-27-4)

Safety Data

• Hazardous Substances Data: 867150-27-4(Hazardous Substances Data)

Upstream product

• 867150-29-6 (4R,6S)-(6-methanesulfonyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-acetic acid ethyl ester 
• 184475-71-6 4-(3-chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline 

Relevant articles and documents

QUINAZOLINE BASED PROTEIN KINASE INHIBITORS

Hydroxy containing quinazoline based derivatives have enhanced and unexpected drug properties as inhibitors of protein kinases and are useful in treating disorders related to abnormal protein kinase activities such as cancer.