86718-01-6

Basic information

• Product Name: Methyl imidazo[1,2-a]pyridine-7-carboxylate
• Synonyms: Methyl imidazo[1,2-a]pyridine-7-carboxylate;IMidazo[1,2-a]pyridine-7-carboxylic acid, Methyl ester;7-(Methoxycarbonyl)imidazo[1,2-a]pyridine;methyl H-imidazo[1,2-a]pyridine-7-carboxylate
• CAS NO: 86718-01-6
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.174
• EINECS: 200-258-5
• Mol File: 86718-01-6.mol
• Article Data: 12

Chemical Properties

• Melting Point: 133-135℃
• Appearance: /
• Density: 1.269 g/cm³
• Storage Temp.: 2-8°C
• PKA: 4.67±0.50(Predicted)
• CAS DataBase Reference: Methyl imidazo[1,2-a]pyridine-7-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl imidazo[1,2-a]pyridine-7-carboxylate(86718-01-6)
• EPA Substance Registry System: Methyl imidazo[1,2-a]pyridine-7-carboxylate(86718-01-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 86718-01-6(Hazardous Substances Data)

Usage

General Description

Methyl imidazo[1,2-a]pyridine-7-carboxylate is a chemical compound with the molecular formula C10H8N2O2, belonging to the class of organic compounds known as imidazo[1,2-a]pyridines. These are organic polycyclic compounds containing an imidazo ring fused to a pyridine ring. Methyl imidazo[1,2-a]pyridine-7-carboxylate is typically used in labs for various research purposes, including the study of its chemical properties and reactions. However, information pertaining to its precise uses, safety profile, or potential applications in industries such as pharmaceuticals or materials science is relatively limited in available literature. This suggests that the compound may primarily be of interest in pure chemistry research contexts rather than applied settings.

Upstream product

• 6937-03-7 methyl 2-aminoisonicotinate 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 107-20-0 2-chloroethanal 
• 7252-83-7 1-bromo-2,2-dimethoxyethane 
• 67-56-1 methanol 
• 648423-85-2 imidazo[1,2-a]pyridine-7-carboxylic acid 

Downstream Products

• 136117-73-2 7-imidazo<1,2-a>pyridinecarboxaldehyde 
• 1009378-93-1 methyl 3-iodoimidazo[1,2-a]pyridine-7-carboxylate 
• 136117-77-6 1-imidazo[1,2-a]pyridin-7-ylpropan-2-one 
• 136117-75-4 7-(2-nitro-1-propenyl)imidazo<1,2-a>pyridine 
• 136117-86-7 (Z)-4-Dimethylamino-3-imidazo[1,2-a]pyridin-7-yl-but-3-en-2-one 
• 136117-90-3 5-Imidazo[1,2-a]pyridin-7-yl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 648423-85-2 imidazo[1,2-a]pyridine-7-carboxylic acid 
• 1019258-66-2 methyl 3-(hydroxymethyl)imidazo[1,2-a]pyridine-7-carboxylate 
• 1207852-89-8 3-(6-chloropyrazin-2-yl)imidazo[1,2-a]pyridine-7-carboxylic acid methyl ester 
• 1220708-85-9 N-butyl-5-(imidazo[1,2-a]pyridin-7-yl)-1,3,4-thiadiazol-2-amine 
• 421595-78-0 imidazo[1,2-a]pyridine-7-carbohydrazide 
• 1201657-65-9 C₁₀H₈N₄O 
• 1251863-83-8 C₁₉H₁₉N₅O₂ 
• 1251863-15-6 {3-isopropoxy-5-[7-(5-methyl[1,3,4]oxadiazol-2-yl)imidazo[1,2-a]pyridin-3-yl]phenyl}urea 

Relevant articles and documents

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES

The present invention discloses compounds according to Formula (I), wherein R1a, R1b, R1c, R2a, W1, W2, X1, X2, X3, Y, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, fibrotic diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformation, diseases involving impairment of bone turnover, diseases associated with hypersecretion of IL-6, diseases associated with hypersecretion of TNFα, interferons, IL-12 and/or IL-23, respiratory diseases, endocrine and/or metabolic diseases, cardiovascular diseases, dermatological diseases, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.

NEW 2-AMIDOTHIADIAZOLE DERIVATIVES

New 2-amidothiadiazole derivatives having the chemical structure of formula (I) or pharmaceutically acceptable salts or N-oxides thereof as agonists of S1P1 receptors.

BICYCLIC HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS

The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, q, A, B, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.