86726-11-6

Basic information

• Product Name: 2-[(E)-4-(2-Hydroxy-3-methyl-phenyl)-but-2-enyl]-malonic acid diethyl ester
• CAS NO: 86726-11-6
• Molecular Weight: 320.386
• Mol File: 86726-11-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(E)-4-(2-Hydroxy-3-methyl-phenyl)-but-2-enyl]-malonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(E)-4-(2-Hydroxy-3-methyl-phenyl)-but-2-enyl]-malonic acid diethyl ester(86726-11-6)
• EPA Substance Registry System: 2-[(E)-4-(2-Hydroxy-3-methyl-phenyl)-but-2-enyl]-malonic acid diethyl ester(86726-11-6)

Safety Data

• Hazardous Substances Data: 86726-11-6(Hazardous Substances Data)

Upstream product

• 7686-78-4 diethyl 2-vinylcyclopropane-1,1-dicarboxylate 
• 95-48-7 ortho-cresol 

Relevant articles and documents

UNUSUAL FRIEDEL-CRAFTS REACTIONS-VI. SYNTHESIS OF ETHYL 6-(2-HYDROXYPHENYL)-2-CARBETHOXY-4-HEXENOATES BY REACTION OF METAL PHENOLATES WITH DIETHYL 2-VINYLCYCLOPROPANE-1,1-DICARBOXYLATES

A mild synthesis of ethyl 6-(2-hydroxyphenyl)-2-carbethoxy-4-hexenoates (4) (SnCl4-promoted o-specific alkylation of potassium phenolates 1 with diethyl vinylcyclopropane-1,1-dicarboxylates 2) involves an oriented hexacoordinated substrate-reagent complex 3, accounting for both o-specific attack on the phenol, and 1,7-homoconjugate addition to the vinylcyclopropane.