867287-84-1

Basic information

• Product Name: 3-Thiophenecarboxylic acid, 4-[([1,1'-biphenyl]-4-ylamino)carbonyl]-2,5-dihydro-
• CAS NO: 867287-84-1
• Molecular Formula: C18H15NO3S
• Molecular Weight: 325.388
• Mol File: 867287-84-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Thiophenecarboxylic acid, 4-[([1,1'-biphenyl]-4-ylamino)carbonyl]-2,5-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenecarboxylic acid, 4-[([1,1'-biphenyl]-4-ylamino)carbonyl]-2,5-dihydro-(867287-84-1)
• EPA Substance Registry System: 3-Thiophenecarboxylic acid, 4-[([1,1'-biphenyl]-4-ylamino)carbonyl]-2,5-dihydro-(867287-84-1)

Safety Data

• Hazardous Substances Data: 867287-84-1(Hazardous Substances Data)

Upstream product

• 75532-25-1 2,2,4,4-tetrahydrothiophene-3,4-dicarboxylic acid anhydride 
• 92-67-1 4-phenylalanine 
• 155251-30-2 3-cyano-3-hydroxy-tetrahydrothiophene-4-carboxylic acid methyl ester 
• 155251-31-3 3-hydroxy-tetrahydro-thiophene-3,4-dicarboxylic acid 
• 2689-68-1 methyl 4-oxotetrahydrothiophene-3-carboxylate 

Relevant articles and documents

SAR, species specificity, and cellular activity of cyclopentene dicarboxylic acid amides as DHODH inhibitors

Novel DHODH inhibitors were developed based on a previously described series by introduction of heteroatoms into the cyclopentene ring and hydroxyl groups attached to it. Also, the hydrophobic biphenyl side chain was replaced with benzyloxy phenyl groups. Activities on human, rat, and mouse enzymes indicate a species specificity of these inhibitors.