867333-30-0

Basic information

• Product Name: 4-(4-BROMO-BENZOYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 4-(4-BROMO-BENZOYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-4-(4-BROMOBENZOYL)PIPERAZINE;tert-Butyl 4-(4-bromobenzoyl)piperazine-1-carboxylate
• CAS NO: 867333-30-0
• Molecular Formula: C₁₆H₂₁BrN₂O₃
• Molecular Weight: 369.25
• Mol File: 867333-30-0.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-BROMO-BENZOYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BROMO-BENZOYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(867333-30-0)
• EPA Substance Registry System: 4-(4-BROMO-BENZOYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(867333-30-0)

Safety Data

• Hazardous Substances Data: 867333-30-0(Hazardous Substances Data)

Upstream product

• 586-75-4 4-chlorobenzoyl chloride 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 586-76-5 4-Bromobenzoic acid 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 910907-90-3 4-[4-(5-nitro-pyrimidin-2-ylamino)-benzoyl]-piperazine-1-carboxylic acid tert-butyl ester 
• 59939-72-9 1-[(4-bromophenyl)carbonyl]piperazine 
• 1018070-76-2 tert-butyl 4-(4-{[7-(2-chloro-5-methoxyphenyl)-5-methyl-1,2,4-benzotriazin-3-yl]amino}benzoyl)piperazine-1-carboxylate 
• 1622867-16-6 C₂₅H₂₁BrN₄O₃S 

Relevant articles and documents

KINASE MODULATORS AND METHODS OF USE THEREOF

The present invention relates to novel compounds that modulate the activity of one or more kinases, such as TYK2 or mutants thereof. The compounds, which may be kinase inhibitors or activators, are useful for treating autoimmune diseases, such as, such as psoriasis, lupus, multiple sclerosis, and inflammatory bowel disease.

Optimization and SAR research at the piperazine and phenyl rings of JNJ4796 as new anti-influenza A virus agents, part 1

JNJ4796, a small molecule fuse inhibitor targeting the conserved stem region of hemagglutinin, effectively neutralized a broad spectrum of group 1 influenza A virus (IAV), and protected mice against lethal and sublethal influenza challenge after oral admi

NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, comprising same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.