86847-63-4 Usage
General Description
2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-2-YL)-PROPIONAMIDE is a chemical compound with the molecular formula C14H24N2OSi. It is a derivative of pyridine and propionamide, containing a silicon atom and two methyl groups. 2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-2-YL)-PROPIONAMIDE is commonly used in organic synthesis and pharmaceutical research due to its potential pharmacological properties. It has been studied for its potential use in the treatment of various diseases and conditions. Additionally, it may have applications in the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 86847-63-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,8,4 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 86847-63:
(7*8)+(6*6)+(5*8)+(4*4)+(3*7)+(2*6)+(1*3)=184
184 % 10 = 4
So 86847-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H22N2OSi/c1-13(2,3)12(16)15-11-10(17(4,5)6)8-7-9-14-11/h7-9H,1-6H3,(H,14,15,16)
86847-63-4Relevant articles and documents
Regiospecific Electrophilic Substitution of Aminopyridines: Ortho Lithiation of 2-, 3-, and 4-(Pivaloylamino)pyridines
Turner, James A.
, p. 3401 - 3408 (2007/10/02)
2- and 4-(pivaloylamino)pyridines have been shown to undergo metalation exclusively at C-3 and these smoothly react with a variety of electrophiles to produce 2,3- and 3,4-disubstituted pyridines, respectively.Removal of the pivaloyl protecting group results in overall electrophilic substitution of an aminopyridine.Utilization of this method is exemplified by efficient syntheses of 2- and 4-aminonicotinaldehydes.Minor modifications of the reaction conditions permitted exclusive ortho metalation of 2-(pivaloylamino)pyridines additionally functionalized by chloro, fluoro, or methyl groups.Although the major product from reaction of 3-(pivaloylamino)pyridine by this method was metalation at C-4, the reaction was complicated by substantial quantities of product derived from nucleophilic attack by n-butyllithium on the pyridine nucleus.
