86847-70-3 Usage
General Description
2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-4-YL)-PROPIONAMIDE is a chemical compound that belongs to the class of propionamides. It is composed of a propionamide core with a dimethyl and a trimethylsilyl-pyridin-4-yl group attached to it. This chemical is important in the field of organic chemistry and pharmaceuticals due to its potential applications. It may be used as a reagent in chemical reactions and as a building block in the synthesis of various compounds. Additionally, it may have biological activities and could be used in the development of new drugs. Further research and testing may be necessary to fully understand the properties and potential uses of this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 86847-70-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,8,4 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 86847-70:
(7*8)+(6*6)+(5*8)+(4*4)+(3*7)+(2*7)+(1*0)=183
183 % 10 = 3
So 86847-70-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H22N2OSi/c1-13(2,3)12(16)15-10-7-8-14-9-11(10)17(4,5)6/h7-9H,1-6H3,(H,14,15,16)
86847-70-3Relevant articles and documents
Regiospecific Electrophilic Substitution of Aminopyridines: Ortho Lithiation of 2-, 3-, and 4-(Pivaloylamino)pyridines
Turner, James A.
, p. 3401 - 3408 (2007/10/02)
2- and 4-(pivaloylamino)pyridines have been shown to undergo metalation exclusively at C-3 and these smoothly react with a variety of electrophiles to produce 2,3- and 3,4-disubstituted pyridines, respectively.Removal of the pivaloyl protecting group results in overall electrophilic substitution of an aminopyridine.Utilization of this method is exemplified by efficient syntheses of 2- and 4-aminonicotinaldehydes.Minor modifications of the reaction conditions permitted exclusive ortho metalation of 2-(pivaloylamino)pyridines additionally functionalized by chloro, fluoro, or methyl groups.Although the major product from reaction of 3-(pivaloylamino)pyridine by this method was metalation at C-4, the reaction was complicated by substantial quantities of product derived from nucleophilic attack by n-butyllithium on the pyridine nucleus.
