86861-32-7

Basic information

• Product Name: N-(2,6-diethyl-4-nitrophenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine
• Synonyms: N-(2,6-diethyl-4-nitrophenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine
• CAS NO: 86861-32-7
• Molecular Weight: 262.312
• Mol File: 86861-32-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(2,6-diethyl-4-nitrophenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-diethyl-4-nitrophenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine(86861-32-7)
• EPA Substance Registry System: N-(2,6-diethyl-4-nitrophenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine(86861-32-7)

Safety Data

• Hazardous Substances Data: 86861-32-7(Hazardous Substances Data)

Upstream product

• 86861-31-6 1-acetyl-N-(2,6-diethylphenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine 
• 4751-48-8 2-(2,6-diethylphenylimino)imidazolidine 
• 579-66-8 2,6-diethylaniline 

Downstream Products

• 121158-54-1 2,6-dibromo-4-[(4,5-dihydro-1H-imidazol-2(3H)-ylidene)amino]-3,5-diethylbenzenamine 
• 121158-55-2 C₁₃H₁₈⁽³⁾H₂N₄ 
• 121158-53-0 N-(4-azido-2,6-diethylphenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine 
• 121158-56-3 N-(4-azido-2,6-diethyl<3,5-(3)H2>phenyl)-4,5-dihydro-1H-imidazol-2(3H)-imine 
• 86861-20-3 2,6-Diethyl-N₁-(2-imidazolidinylidene)-1,4-benzenediamine 

Relevant articles and documents

A probe for octopamine receptors: Synthesis of 2-[(4-azido-2,6-diethylphenyl)imino]imidazolidine and its tritiated derivative, a potent reversible-irreversible activator of octopamine-sensitive adenylate cyclase

In order to develop an irreversible ligand for octopamine receptors, a highly potent azido-substituted 2-(phenylimino)imidazolidine (NC-5Z, 8) and its tritiated derivative (3H-NC-5Z, 11) have been designed and synthesized. Under reversible-binding conditions, NC-5Z is 50-100-fold more potent than octopamine in activating octopamine-sensitive adenylate cyclase in a variety of tissues. After photolysis, 3H-NC-5Z binds irreversibly to cell membranes, and this binding is reduced by preincubation with octopamine agonists and antagonists but not by norepinephrine, dopamine, serotonin, or histamine. NC-5Z should be useful both as a potent reversible octopamine agonist and as an affinity probe for characterizing and isolating octopamine-receptor proteins.

Method of lowering intraocular pressure using phenylimino-imidazoles

A method is provided of treating glaucoma in a patient which comprises administering, preferably as eye drops, an effective amount of the compound STR1 which is preferably in the form of its hydrochloride. The compound is administered preferably in the form of a sterile pharmacologically acceptable solution which contains from 0.1 to 5, and more preferably 0.1 to 2.0, percent by weight of said compound. The patient preferably obtains the anti-glaucoma agent in the form of a kit which comprises the sterile pharmacologically acceptable solution and an eyedropper for dispensing said sterile pharmacologically acceptable solution to the affected eyes of a patient suffering from glaucoma.