868629-78-1 Usage
Description
2-(5-Bromo-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a chemical compound that is widely used in organic synthesis, particularly in the pharmaceutical and agrochemical industries. It is a boronic ester, which makes it a valuable reagent for Suzuki-Miyaura coupling reactions, allowing for the formation of carbon-carbon bonds. Known for its stability and low toxicity, it is a preferred choice for many synthetic applications. Its unique molecular structure and properties have positioned it as a key building block in the development of various biologically active molecules.
Uses
Used in Pharmaceutical Industry:
2-(5-Bromo-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used as a reagent for Suzuki-Miyaura coupling reactions to form carbon-carbon bonds in the synthesis of pharmaceutical compounds. Its stability and low toxicity make it a preferred choice for the development of biologically active molecules.
Used in Agrochemical Industry:
2-(5-Bromo-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used as a reagent for Suzuki-Miyaura coupling reactions in the synthesis of agrochemical compounds. Its unique molecular structure and properties contribute to the development of effective and stable agrochemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 868629-78-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,8,6,2 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 868629-78:
(8*8)+(7*6)+(6*8)+(5*6)+(4*2)+(3*9)+(2*7)+(1*8)=241
241 % 10 = 1
So 868629-78-1 is a valid CAS Registry Number.
868629-78-1Relevant articles and documents
Ortho-Selective C-H Borylation of Aromatic Ethers with Pinacol-borane by Organo Rare-Earth Catalysts
Xue, Can,Luo, Yong,Teng, Huailong,Ma, Yuanhong,Nishiura, Masayoshi,Hou, Zhaomin
, p. 5017 - 5022 (2018/05/14)
The regioselective C-H borylation of aromatic ethers such as anisoles is of much interest and importance, but has remained a challenge to date. We report herein the catalytic ortho-selective C-H borylation of a wide range of aromatic ethers with pinacolborane (HBpin) by rare-earth metallocene complexes. This protocol offers an efficient and straightforward route for the synthesis of a variety of borylated aromatic ether derivatives. A proper metal/ligand combination for the rare-earth metal catalysts was found to be critically important to promote this transformation.
Metal-free halogenation of arylboronate with N-halosuccinimide
Kamei, Toshiyuki,Ishibashi, Aoi,Shimada, Toyoshi
, p. 4245 - 4247 (2014/07/22)
Efficient bromination and chlorination of aryl pinacol boronates were accomplished without the addition of metal reagent. The reaction proceeded efficiently with electron-rich arylboronates or heteroarylboronates in DMF or acetonitrile, to afford mono-, d
