86923-98-0
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Basic information
- Product Name: BETA-NERVE GROWTH FACTOR, HUMAN
- Synonyms: HUMAN B-NGF;HUMAN BETA NERVE GROWTH FACTOR;HUMAN BETA-NGF;HUMAN BETA-NGF PROBE;HUMAN NGF-BETA;BETA-NGF (HUMAN);BETA-NERVE GROWTH FACTOR, HUMAN;BETA-NERVE GROWTH FACTOR, HUMAN, RECOMBINANT
- CAS NO:86923-98-0
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
- Mol File: 86923-98-0.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /lyophilized powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: BETA-NERVE GROWTH FACTOR, HUMAN(CAS DataBase Reference)
- NIST Chemistry Reference: BETA-NERVE GROWTH FACTOR, HUMAN(86923-98-0)
- EPA Substance Registry System: BETA-NERVE GROWTH FACTOR, HUMAN(86923-98-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: WGK Germany : 3:;
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 86923-98-0(Hazardous Substances Data)
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86923-98-0 Usage
Uses
NGF-β human has been used:in protein pin arraysto induce U87-MG (glioblastoma cell line) cell proliferationin drug release kineticsGeneral Description
NGFβ (nerve growth factor β) is a protein involved in signal transduction, and expressed by multiple tissues such as placenta, urothelium and bladder smooth muscle cells. It is a neurotrophin and belongs to the NGF family.Biochem/physiol Actions
NGFβ (nerve growth factor β) is essential for the differentiation and survival of neurons. It also plays a key role in the development and maintenance of nervous system. It is also involved in angiogenesis, and facilitates tumorigenesis such as, oral, breast and prostate cancers. It has potential as marker for the diagnosis of interstitial cystitis/painful bladder syndrome (IC/PBS) and overactive bladder (OAB), and might also aid in determining the therapy for the same. It might be involved in changes in placental function, as NGF signaling is influenced by antenatal depression and selective serotonin reuptake inhibitor (SSRI) treatment.Check Digit Verification of cas no
The CAS Registry Mumber 86923-98-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,9,2 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.Calculate Digit Verification of CAS Registry Number 86923-98:
(7*8)+(6*6)+(5*9)+(4*2)+(3*3)+(2*9)+(1*8)=180
180 % 10 = 0
So 86923-98-0 is a valid CAS Registry Number.
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BETA-NERVE GROWTH FACTOR, HUMAN
