869295-71-6

Basic information

• Product Name: 4-[2-({6-fluoro-2-[({[3-(methoxy)phenyl]methyl}amino)carbonyl]-4-oxo-3,4-dihydroquinazolin-5-yl}oxy)ethyl]benzoic acid
• Synonyms: 4-[2-({6-fluoro-2-[({[3-(methoxy)phenyl]methyl}amino)carbonyl]-4-oxo-3,4-dihydroquinazolin-5-yl}oxy)ethyl]benzoic acid
• CAS NO: 869295-71-6
• Molecular Weight: 491.476
• Mol File: 869295-71-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[2-({6-fluoro-2-[({[3-(methoxy)phenyl]methyl}amino)carbonyl]-4-oxo-3,4-dihydroquinazolin-5-yl}oxy)ethyl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-({6-fluoro-2-[({[3-(methoxy)phenyl]methyl}amino)carbonyl]-4-oxo-3,4-dihydroquinazolin-5-yl}oxy)ethyl]benzoic acid(869295-71-6)
• EPA Substance Registry System: 4-[2-({6-fluoro-2-[({[3-(methoxy)phenyl]methyl}amino)carbonyl]-4-oxo-3,4-dihydroquinazolin-5-yl}oxy)ethyl]benzoic acid(869295-71-6)

Safety Data

• Hazardous Substances Data: 869295-71-6(Hazardous Substances Data)

Upstream product

• 869295-00-1 5,6-difluoro-N-{[3-(methyloxy)phenyl]methyl}-4-oxo-3,4-dihydroquinazoline-2-carboxamide 
• 46112-46-3 4-(2-((tert-butyldimethylsilyl)oxy)ethyl)benzoic acid 

Relevant articles and documents

SUBSTITUTED 2- AMIDOQUINAZOL-4-ONES AS MATRIX METALLOPROTEINASE-13 INHIBITORS

The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]2 hydroxypropyl}5,6 dimethyl 4 oxo 1,4 dihydrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.