86940-97-8

Basic information

• Product Name: 1,3-Dioxolane-4-methanol, 2,2,4-trimethyl-, (R)-
• CAS NO: 86940-97-8
• Molecular Formula: C7H14O3
• Molecular Weight: 146.186
• Mol File: 86940-97-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane-4-methanol, 2,2,4-trimethyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane-4-methanol, 2,2,4-trimethyl-, (R)-(86940-97-8)
• EPA Substance Registry System: 1,3-Dioxolane-4-methanol, 2,2,4-trimethyl-, (R)-(86940-97-8)

Safety Data

• Hazardous Substances Data: 86940-97-8(Hazardous Substances Data)

Upstream product

• 86884-92-6 (R)-(-)-2,2,4-trimethyl-4-<(phenylthio)methyl>-1,3-dioxolane 
• 108-30-5 succinic acid anhydride 
• 86884-87-9 (4RS)-4-hydroxymethyl-2,2,4-trimethyl-1,3-dioxolane 
• 2146-71-6 vinyl laurate 
• 123-20-6 vinyl n-butyrate 
• 1255920-99-0 C₁₅H₂₀O₅ 
• 86884-92-6 (S)-(+)-2,2,4-trimethyl-4-<(phenylthio)methyl>-1,3-dioxolane 
• 86884-93-7 (S)-2,2,4-trimethyl-4-<(phenylsulfinyl)methyl>-1,3-dioxolane 
• 126971-16-2 methyl 2,2,4-trimethyl-1,3-dioxolane-4-carboxylate 
• 149563-84-8 <(S)-2,2,4-trimethyl-1,3-dioxolan-4-yl>methyl butyrate 
• 109240-68-8 4-benzyloxymethyl-2,2,4-trimethyl-1,3-dioxolane 
• 111219-30-8 Phenyl-acetic acid 2,2,4-trimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 138489-59-5 2-[(1R,2S,5R)-2-Isopropyl-5-methyl-1-((R)-2,2,4-trimethyl-[1,3]dioxolan-4-ylmethoxy)-cyclohexyl]-1-phenyl-ethanone 
• 86884-88-0 (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-1-carboxylic acid (S)-2,2,4-trimethyl-[1,3]dioxolan-4-ylmethyl ester 

Downstream Products

• 79243-92-8 (S)-(-)-2,2,4-trimethyl-1,3-dioxolane-4-carboxaldehyde 
• 109240-68-8 4-benzyloxymethyl-2,2,4-trimethyl-1,3-dioxolane 
• 936328-97-1 methyl 2-(4-fluoro-2-{[(4R)-2,2,4-trimethyl-1,3-dioxolan-4-yl]methoxy}phenyl)propanoate 
• 956599-48-7 4-nitro-3-(2,2,4-trimethyl-[1,3]dioxolan-4-ylmethoxy)-phenol 
• 133868-48-1 <(S)-2,2,4-trimethyl-1,3-dioxolan-4-yl>methyl p-toluenesulfonate 

Relevant articles and documents

Chemoenzymatic enantioselective synthesis of 2-substituted glycerol derivatives

2-Substituted glycerol derivatives 4a-g were resolved by acylation with vinyl butyrate in the presence of lipases in organic media. The reverse reaction, the enzymatic hydrolysis of the corresponding butyrates 5a-g, was also highly stereoselective and pro

Development of a multikilogram synthesis of a chiral epoxide precursor to a CCR1 antagonist. Use of in situ monitoring for informed optimisation via fragile intermediates

The optimisation and scale up of a manufacturing route to a key intermediate, acetic acid 4-acetylamino-3-(2-methyl-oxiranyl- methoxy)phenyl ester (2), utilising a SNAr coupling, the hydro- genation of a nitro moiety and the conversion of a chi

An alternative approach to (S)- and (R)-2-methylglycidol O-benzyl ether derivatives

This report describes the gram scale synthesis of (S)- and (R)-2,2,4-trimethyl-4-(hydroxymethyl)-1,3-dioxolanes using the Sharpless asymmetric dihydroxylation (AD) of the Weinreb amide of 2-methyl-2-propenoic acid. The 2-methylglycerol acetonides resultan