86971-16-6

Basic information

• Product Name: (+/-)-1-phenyl-2-<(phenylthio)methyl>piperidine
• Synonyms: (+/-)-1-phenyl-2-<(phenylthio)methyl>piperidine
• CAS NO: 86971-16-6
• Molecular Weight: 283.437
• Mol File: 86971-16-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-1-phenyl-2-<(phenylthio)methyl>piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-1-phenyl-2-<(phenylthio)methyl>piperidine(86971-16-6)
• EPA Substance Registry System: (+/-)-1-phenyl-2-<(phenylthio)methyl>piperidine(86971-16-6)

Safety Data

• Hazardous Substances Data: 86971-16-6(Hazardous Substances Data)

Upstream product

• 86971-14-4 Hex-5-enyl-phenyl-amine; hydrochloride 
• 931-59-9 benzenesulfenyl chloride 

Downstream Products

• 14142-16-6 (+/-)-2-methyl-1-phenylpiperidine 

Relevant articles and documents

Novel Synthesis of the Pyrrolizidine Skeleton by Sulfenocycloamination. Total Synthesis of (+/-)-Retronecine and (+/-)-Turneforcidine

The ω-unsaturated amines 1, 6, and 7 were converted into pyrrolidines 4 and 8 and piperidine 9, respectively, by treatment of their hydrochlorides with benzenesulfenyl chloride followed by base-induced ring closure.This novel sulfenocycloamination ring closure was applied to the synthesis of the pyrrolizidine ring (e.g., 20) and to the total synthesis of (+/-)-retronecine (32) and (+/-)-turneforcidine (34).