869985-78-4

Basic information

• Product Name: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester
• Synonyms: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester
• CAS NO: 869985-78-4
• Molecular Weight: 488.564
• Mol File: 869985-78-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester(869985-78-4)
• EPA Substance Registry System: 12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester(869985-78-4)

Safety Data

• Hazardous Substances Data: 869985-78-4(Hazardous Substances Data)

Upstream product

• 278593-17-2 1-(phenylsulfonyl)-1H-indole-3-carboxylic acid 
• 39959-51-8 2-iodobenzylamine 
• 923603-92-3 N-(2-iodobenzyl)-1-(phenylsulfonyl)-1H-indole-3-carboxamide 

Relevant articles and documents

Synthesis of latonduine derivatives via intramolecular Heck?reaction

The synthesis of indole ring-fused benzazepinone series as latonduine derivatives has been developed via an intramolecular Heck reaction. The scope has been enlarged not only to indole moiety but also to pyrrolo and benzo[b]thiophene nuclei. Several derivatives prepared have been evaluated in vitro for their antiproliferative activities on breast cancer cell lines. Some of them showed promising cytotoxic activities.