87038-06-0

Basic information

• Product Name: (-)-Lofexidine hydrochloride
• Synonyms: (-)-Lofexidine hydrochloride
• CAS NO: 87038-06-0
• Molecular Weight: 295.596
• Mol File: 87038-06-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-Lofexidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-Lofexidine hydrochloride(87038-06-0)
• EPA Substance Registry System: (-)-Lofexidine hydrochloride(87038-06-0)

Safety Data

• Hazardous Substances Data: 87038-06-0(Hazardous Substances Data)

Upstream product

• 81447-78-1 (-)-Lofexidine 

Relevant articles and documents

ENANTIOSELECTIVE SYNTHESIS OF (+) AND (-)-2-[1-(2,6-DICHLOROPHENOXY)-ETHYL]-1,3-DIAZACYCLOPENT-2-3ENE

This application provides a method for the enantioselective synthesis of (+) and (?) lofexidine or 2-[1-(2,6)-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene.

A scalable, enantioselective synthesis of the r2-adrenergic agonist, lofexidine

A scalable and high-yielding synthetic route toward pure enantiomers of the α2-adrenergic agonist, lofexidine hydrochloride, is presented. Salient features include a rapid one-pot amide alkylation-imidazoline formation sequence on the carboxami