870521-33-8

Basic information

• Product Name: 2-Morpholinopyrimidin-5-ylboronic acid
• Synonyms: 2-morpholinopyrimidin-5-ylboronic acid;[2-(4-Morpholinyl)-5-pyrimidinyl]boronic acid;2-Morpholinopyrimidine-5-boronic acid;Boronic acid,B-[2-(4-morpholinyl)-5-pyrimidinyl]-;2-(Morpholine-4-yl)pyrimidine-5-boronic acid;2-morpholino-5-pyrimidineboronic acid
• CAS NO: 870521-33-8
• Molecular Formula: C₈H₁₂BN₃O₃
• Molecular Weight: 209.01
• Mol File: 870521-33-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 484 °C at 760 mmHg
• Flash Point: 246.5 °C
• Appearance: /
• Density: 1.37
• Refractive Index: 1.583
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: 2-Morpholinopyrimidin-5-ylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Morpholinopyrimidin-5-ylboronic acid(870521-33-8)
• EPA Substance Registry System: 2-Morpholinopyrimidin-5-ylboronic acid(870521-33-8)

Safety Data

• Hazardous Substances Data: 870521-33-8(Hazardous Substances Data)

Usage

General Description

2-Morpholinopyrimidin-5-ylboronic acid is a chemical compound used in the field of organic synthesis and medicinal chemistry. It is a boronic acid derivative that contains a morpholinopyrimidine group. 2-Morpholinopyrimidin-5-ylboronic acid has been investigated for its potential as a pharmaceutical intermediate and as a building block for the synthesis of various biologically active molecules. It is known for its ability to form stable complexes with diols and has been used in the development of novel chemical reactions and drug discovery efforts. Additionally, it has been studied for its potential use in the treatment of neurological disorders and cancer. Overall, 2-Morpholinopyrimidin-5-ylboronic acid is a versatile and valuable chemical that has numerous applications in the field of chemistry and medicine.

InChI:InChI=1/C8H12BN3O3/c13-9(14)7-5-10-8(11-6-7)12-1-3-15-4-2-12/h5-6,13-14H,1-4H2

Upstream product

• 84539-22-0 4-(5-bromopyrimidin-2-yl)morpholine 
• 110-91-8 morpholine 
• 1003845-06-4 (2-chloropyrimidin-5-yl)boronic acid 

Downstream Products

• 1206797-72-9 C₂₄H₂₃N₃O₄S₂ 
• 1206797-76-3 C₂₄H₂₃N₃O₄S₂ 
• 1435972-29-4 C₂₇H₃₃N₇O₄ 

Relevant articles and documents

FUSED IMIDAZOLE AND PYRAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY

A series of substituted benzimidazole, imidazo[1,2-a]pyridine and pyrazolo[1,5-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY

A series of substituted fused tricyclic imidazole derivatives, in particular dihydro- 1H-pyrano[4',3':4,5]imidazo[1,2-a]pyridine, 1,2,3,4-tetrahydroimidazo[1,2-a:5,4- c']dipyridine, dihydro-1H-pyrano[3',4':4,5]imidazo[1,2-a]pyridine and tetrahydro-6H- cyc

FUSED TRICYCLIC BENZIMIDAZOLES DERIVATIVES AS MODULATORS OF TNF ACTIVITY

A series of tricyclic benzimidazole derivatives, in particular dihydro-1H- imidazo [1,2-a]benzimidazo le, dihydro-1H-pyrrolo [1,2-a]benzimidazo le, dihydro-1H- pyrazino[1,2-a]benzimidazole, dihydro-1H-[1,4]oxazino[4,3-a]benzimidazole and dihydrothiazolo[3,4-a]benzimidazolem, and analogues thereof, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.