870724-41-7Relevant articles and documents
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8. {2-[2-(4-chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of α1D- and α1B-adrenore
Quaglia, Wilma,Santoni, Giorgio,Pigini, Maria,Piergentili, Alessandro,Gentili, Francesco,Buccioni, Michela,Mosca, Michela,Lucciarini, Roberta,Amantini, Consuelo,Nabissi, Massimo Ivan,Ballarini, Patrizia,Poggesi, Elena,Leonardi, Amedeo,Giannella, Mario
, p. 7750 - 7763 (2007/10/03)
A series of new α1-adrenoreceptor antagonists (5-18) was prepared by introducing various substituents (Topliss approach) into the ortho, meta, and para positions of the benzyloxy function of the phendioxan open analogue 4 ("openphendioxan"). Al