870854-85-6

Basic information

• Product Name: 4-methoxy-1-methyl-3-(phenylsulfonyl)pyridin-2(1H)-one
• Synonyms: 4-methoxy-1-methyl-3-(phenylsulfonyl)pyridin-2(1H)-one
• CAS NO: 870854-85-6
• Molecular Weight: 279.317
• Mol File: 870854-85-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-methoxy-1-methyl-3-(phenylsulfonyl)pyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxy-1-methyl-3-(phenylsulfonyl)pyridin-2(1H)-one(870854-85-6)
• EPA Substance Registry System: 4-methoxy-1-methyl-3-(phenylsulfonyl)pyridin-2(1H)-one(870854-85-6)

Safety Data

• Hazardous Substances Data: 870854-85-6(Hazardous Substances Data)

Upstream product

• 7605-28-9 2-(phenylsulfonyl)acetonitrile 
• 870854-86-7 3-Methoxy-3-methyl-2-benzenesulfonylpropenenitrile 
• 870854-88-9 4-methoxy-3-(phenylsulfonyl)pyridin-2(1H)-one 
• 74-88-4 methyl iodide 

Downstream Products

• 41759-19-7 4-methoxy-1-methyl-2-pyridone 

Relevant articles and documents

A practical procedure for the selective N-alkylation of 4-alkoxy-2-pyridones and its use in a sulfone-mediated synthesis of N-methyl-4-methoxy-2-pyridone

It has been found that selective N-alkylation of 4-alkoxy-2-pyridones can be achieved under anhydrous, mild conditions with tetrabutylammonium iodide and potassium tert-butoxide being employed as the catalyst and the base, respectively. The procedure was applied to the preparation of 4-methoxy-1-methyl-2-pyridone, a valuable building block for heterocycle synthesis.