871332-81-9 Usage
General Description
3-Nitro-5-(pyrrolidin-1-ylcarbonyl)benzenboronic acid is a chemical compound with the molecular formula C14H15BN2O6. It is a boronic acid derivative with a nitro and pyrrolidinylcarbonyl functional group attached to a benzene ring, making it a versatile building block for the synthesis of various pharmaceuticals and agrochemicals. 3-NITRO-5-(PYRROLIDIN-1-YLCARBONYL)BENZENEBORONIC ACID is commonly used as a reagent in organic synthesis and medicinal chemistry, particularly in the development of potential anti-cancer and anti-inflammatory drugs. Its unique structure and properties make it valuable for the development of new drugs and materials in the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 871332-81-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,3,3 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 871332-81:
(8*8)+(7*7)+(6*1)+(5*3)+(4*3)+(3*2)+(2*8)+(1*1)=169
169 % 10 = 9
So 871332-81-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H13BN2O5/c15-11(13-3-1-2-4-13)8-5-9(12(16)17)7-10(6-8)14(18)19/h5-7,16-17H,1-4H2
871332-81-9Relevant articles and documents
A robust three-step telescoped synthesis of electron-deficient amide substituted arylboronic acids
Zhu, Jason,Razler, Thomas M.,Xu, Zhongmin,Conlon, David A.,Sortore, Eric W.,Fritz, Alan W.,Demerzhan, Roman,Sweeney, Jason T.
scheme or table, p. 438 - 442 (2012/02/03)
A robust three-step telescoped process for the preparation of electron-deficient amide-substituted arylboronic acids from readily available bromobenzoic acids has been developed. An EDC-HOBT-promoted amide formation of a bromobenzoic acid was followed by subjection of the product stream to a palladium-mediated cross-coupling with B2(pin)2. The resultant mixture of the arylboronate ester and arylboronic acid was directly treated with NaIO4, followed by a heptane-MeTHF crystallization, to cleanly afford the corresponding arylboronic acid in good yield. This general procedure was used to synthesize electron-deficient amide-substituted arylboronic acids with a diverse array of electron-withdrawing substituents.
