871351-88-1 Usage
Description
1-(2,3-dichlorophenyl)-4-propyl-piperazine, also known as DF 203, is a chemical compound belonging to the class of piperazine derivatives. It is a psychoactive substance that functions as a selective serotonin reuptake inhibitor (SSRI), which is being investigated for its potential therapeutic use in treating depression and anxiety disorders. DF 203 has demonstrated anxiolytic and antidepressant properties in preclinical studies, with its mechanism of action centered on modulating serotonin levels in the brain. Despite its potential benefits, the compound also carries a risk of abuse and dependence, leading to its restricted and controlled status in many countries due to its psychoactive effects and potential for misuse.
Uses
Used in Pharmaceutical Industry:
1-(2,3-dichlorophenyl)-4-propyl-piperazine is used as a therapeutic agent for the treatment of depression and anxiety disorders due to its anxiolytic and antidepressant properties. Its action as a selective serotonin reuptake inhibitor (SSRI) makes it a promising candidate for modulating serotonin levels in the brain, which is crucial for managing the symptoms of these conditions.
Used in Research and Development:
In the field of neuroscience and pharmacology, 1-(2,3-dichlorophenyl)-4-propyl-piperazine serves as a research compound for understanding the role of serotonin in mood regulation and the potential development of new treatments for mood disorders. Its psychoactive properties and mechanism of action provide valuable insights into the complex interactions between neurotransmitters and mental health.
Used in Regulatory and Legal Frameworks:
Due to the potential for abuse and dependence associated with 1-(2,3-dichlorophenyl)-4-propyl-piperazine, it is used as a case study in the development and implementation of regulatory and legal frameworks to control the distribution and use of psychoactive substances. This helps ensure public safety and prevent misuse while still allowing for its potential therapeutic applications to be explored and utilized.
Check Digit Verification of cas no
The CAS Registry Mumber 871351-88-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,3,5 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 871351-88:
(8*8)+(7*7)+(6*1)+(5*3)+(4*5)+(3*1)+(2*8)+(1*8)=181
181 % 10 = 1
So 871351-88-1 is a valid CAS Registry Number.
871351-88-1Relevant articles and documents
Molecular determinants of selectivity and efficacy at the dopamine D3 receptor
Newman, Amy Hauck,Beuming, Thijs,Banala, Ashwini K.,Donthamsetti, Prashant,Pongetti, Katherine,Labounty, Alex,Levy, Benjamin,Cao, Jianjing,Michino, Mayako,Luedtke, Robert R.,Javitch, Jonathan A.,Shi, Lei
experimental part, p. 6689 - 6699 (2012/09/25)
The dopamine D3 receptor (D3R) has been implicated in substance abuse and other neuropsychiatric disorders. The high sequence homology between the D3R and D2R, especially within the orthosteric binding site (OBS) that binds dopamine, has made the developm
