871476-72-1

Basic information

• Product Name: Benzenamine, 4-(3-amino-3-methyl-1-butynyl)-2-chloro-
• CAS NO: 871476-72-1
• Molecular Formula: C11H13ClN2
• Molecular Weight: 208.691
• Mol File: 871476-72-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-(3-amino-3-methyl-1-butynyl)-2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-(3-amino-3-methyl-1-butynyl)-2-chloro-(871476-72-1)
• EPA Substance Registry System: Benzenamine, 4-(3-amino-3-methyl-1-butynyl)-2-chloro-(871476-72-1)

Safety Data

• Hazardous Substances Data: 871476-72-1(Hazardous Substances Data)

Upstream product

• 42016-93-3 2-chloro-4-iodoaniline 
• 2978-58-7 1,1-dimethylprop-3-ynylamine 

Downstream Products

• 871473-26-6 C₂₃H₂₂Cl₂N₆OS 
• 871476-73-2 C₁₆H₂₁ClN₂O₂ 

Relevant articles and documents

Non-nucleoside reverse transcriptase inhibitors

The present invention provides for compounds useful for treating an HIV infection, or preventing an HIV infection, or treating AIDS or ARC. The compounds of the invention are of formula I wherein R1, R2, R3, R4, X1 and X2 are as herein defined. Also disclosed in the present invention are methods of treating an HIV infection with compounds defined herein and pharmaceutical compositions containing said compounds.

NON NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS

The invention relates to compounds of formula (I) wherein Ar, X, R1, R2, R3 and R4 are as defined herein and, pharmaceutical compositions thereof useful, either alone or in combination with other therapeutic agents as reverse transcriptase inhibitors against wild type and single or double mutant strains of HIV for the treatment or prophylaxis of HIV infection