87154-28-7Relevant articles and documents
Synthesis and evaluation of 3-halocyclophosphamides and analogous compounds as novel anticancer 'pro-prodrugs'
Zon,Ludeman,Ozkan,Chandrasegaran,Hammer,Dickerson,Mizuta,Egan
, p. 687 - 691 (2007/10/02)
3-Fluoro-, 3-chloro-, and 3-bromocyclophosphamide were prepared from the reaction of trifluoromethylhypofluorite, sodium hypochlorite, and bromine with the anticancer drug cyclophosphamide. Treatment of cis-, and trans-4-phenylcyclophosphamide and 5,6-ben