871825-54-6

Basic information

• Product Name: [3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL
• Synonyms: [3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL;[3-(1H-1,2,4-Triazol-1-ylmethyl)phenyl]methanol 97%;3-[(1H-1,2,4-Triazol-1-yl)methyl]benzyl alcohol 97%;3-[(1H-1,2,4-Triazol-1-yl)methyl]benzylalcohol97%
• CAS NO: 871825-54-6
• Molecular Formula: C₁₀H₁₁N₃O
• Molecular Weight: 189.21
• Mol File: 871825-54-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 56 °C
• Boiling Point: 411.9°C at 760 mmHg
• Flash Point: 202.9°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 1.59E-07mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: [3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL(871825-54-6)
• EPA Substance Registry System: [3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL(871825-54-6)

Safety Data

• Hazardous Substances Data: 871825-54-6(Hazardous Substances Data)

Usage

General Description

[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL, also known as Triazolphenylmethanol, is a chemical compound with the molecular formula C10H10N2O. It consists of a phenyl group attached to a triazolylmethyl moiety, with a methanol substituent. [3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL is commonly used in organic synthesis and pharmaceutical research, where it serves as a building block for the preparation of various biologically active compounds and pharmaceutical drugs. Triazolphenylmethanol has potential applications in the development of new drugs for the treatment of various medical conditions, including cancer and infectious diseases. Furthermore, it is also used as a research tool in the study of chemical and biological processes.

InChI:InChI=1/C10H11N3O/c14-6-10-3-1-2-9(4-10)5-13-8-11-7-12-13/h1-4,7-8,14H,5-6H2

Upstream product

• 857284-24-3 methyl 3-(1H-1,2,4-triazol-1-ylmethyl)benzoate 

Relevant articles and documents

1,2,4-TRIAZOL-l-YL BISPHENYL DERIVATIVES FOR USE IN THE TREATMENT OF ENDOCRINE-DEPENDENT TUMOURS

There is provided a compound of Formula I wherein R3, R4, R5, R6 and R7 are independently selected from H and -Y-R6; wherein each R8 is independently selected from -OH, hydrocarbyl groups, oxyhydrocarbyl groups, cyano (-CN), nitro (-NO2), H-bond acceptors, and halogens; wherein at Jeast one of R3, R4, R5, R6 and R7 is -Y-R8 wherein R8 is selected from substituted and unsubstituted ? heterocyclic rings and amino substituted phenyl groups, wherein X is a bond or a linker group; wherein Y is an optional linker group; and wherein ring A is optionally further , substituted; wherein R9 is selected from H, -OH and -OSO2NR1R2; wherein R1 and R2 are independently selected from H and hydrocarbyl; wherein (a) X is a bond and at least one of R3, R4, R5, R6 and R7 is -Y-R8; OR (b) R9 is -OSO2NR1R2 or - OH and four of R3, R4, R5, R6 and R7 are H and one of R3, R4, R5, R6 and R7 is -Y-R8. These compounds inhibit steroid sulphatase and aronatase activity and are useful in the treatment of endocrine-dependent tumours.