871890-63-0

Basic information

• Product Name: N-methyl-N-phenyl-6-aminoquinoline
• Synonyms: N-methyl-N-phenyl-6-aminoquinoline
• CAS NO: 871890-63-0
• Molecular Weight: 234.301
• Mol File: 871890-63-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-methyl-N-phenyl-6-aminoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-phenyl-6-aminoquinoline(871890-63-0)
• EPA Substance Registry System: N-methyl-N-phenyl-6-aminoquinoline(871890-63-0)

Safety Data

• Hazardous Substances Data: 871890-63-0(Hazardous Substances Data)

Upstream product

• 426265-40-9 quinolin-6-yl 4-methylbenzene-1-sulfonate 
• 100-61-8 N-methylaniline 
• 5263-87-6 6-methoxy quinoline 
• 612-57-7 6-chloroquinoline 

Relevant articles and documents

Aryl-Diadamantyl Phosphine Ligands in Palladium-Catalyzed Cross-Coupling Reactions: Synthesis, Structural Analysis, and Application

Synthesis, temperature-dependent NMR structure investigation and utilization of a new, stable and easily accessible aryl-diadamantylphosphine ligand family is reported. The bulky and electron-rich phosphorus center of the ligand enhances the catalytic activity of palladium in cross-coupling reactions of sterically demanding ortho-substituted aryl halides. In our study, we demonstrated the synthetic applicability of the new phosphine ligands in Buchwald-Hartwig and tosyl hydrazone coupling reactions.

COMPLEXES

The present invention provides apalladium(II)complex of formula (1) or a palladium(II) complex of formula (2). R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R18, R19, R20, R21, R22, R23 and R24, m, E and X are described in the specification. The invention also provides a process for the preparation of the complexes, and their use in carbon-carbon and carbon-heteroatom coupling reactions.

Ni(0)/NHC-catalyzed amination of N-heteroaryl methyl ethers through the cleavage of carbonoxygen bonds

Ni(0)/NHC-based catalyst system can promote the amination of N-heteroaryl methyl ethers via the cleavage of normally unreactive carbon-oxygen bonds. Electron-deficient N-heteroarenes including pyridine, quinoline, isoquinoline, and quinoxaline undergo amination to afford aminopyridine and related heteroarenes, which constitute an important class of compounds.