87212-60-0

Basic information

• Product Name: 2,2-dimethyl-5-(3,4,5-trimethoxybenzylidene)-1,3-dioxane-4,6-dione
• Synonyms: 2,2-dimethyl-5-(3,4,5-trimethoxybenzylidene)-1,3-dioxane-4,6-dione
• CAS NO: 87212-60-0
• Molecular Formula: C₁₆H₁₈O₇
• Molecular Weight: 322.30992
• Mol File: 87212-60-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-dimethyl-5-(3,4,5-trimethoxybenzylidene)-1,3-dioxane-4,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-5-(3,4,5-trimethoxybenzylidene)-1,3-dioxane-4,6-dione(87212-60-0)
• EPA Substance Registry System: 2,2-dimethyl-5-(3,4,5-trimethoxybenzylidene)-1,3-dioxane-4,6-dione(87212-60-0)

Safety Data

• Hazardous Substances Data: 87212-60-0(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 

Downstream Products

• 25173-72-2 3-(3,4,5-trimethoxyphenyl)propanoic acid 
• 1169681-74-6 methyl 4,4,4-trifluoro-3-(3,4,5-trimethoxyphenyl)butanoate 
• 1310812-21-5 C₁₃H₁₇NO₆ 
• 7251-01-6 3,4,5-trimethoxybenzaldehyde N-[-(3,4,5-trimethoxyphenyl)methylidene]hydrazone 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 

Relevant articles and documents

Bentonite catalyzed an efficient and green synthesis of arylidene meldrum's acid derivatives in aqueous media

In the present paper, a simple, highly efficient, and environmentally friendly protocol was proposed for the Knoevenagel condensation reaction of aromatic aldehydes using Meldrum’s acid (2,2-dimethyl-4,6-dioxo-1,3-dioxane) with bentonite as an available n

Microwave-associate synthesis of Co3O4 nanoparticles as an effcient nanocatalyst for the synthesis of arylidene barbituric and Meldrum's acid derivatives in green media

In this study, Co3O4 nanocatalysts were constructed in environmentally appropriate conditions using controlled, effective, and facile microwave method. The final nanostructures were characterized by SEM, XRD, and TEM analyses. The products had a small size distribution, homogeneous morphology, and crystallographic structures associated with the formation of Co3O4 nanostructures. Moreover, EDS mapping analysis confirmed the existence of Co and O elements in the final structure, and the magnetic properties of the samples were investigated by VSM. The application of this nanostructure in a catalytic process was further examined, and the results suggested that it could be used as a novel candidate for the synthesis of arylidene barbituric and Meldrum,s acid through Knoevenagel condensation of aldehydes by barbituric and Meldrum,s acid in aqueous media. The high yield of these nanocatalysts would be justified by the nature of the nanostructure as well as the experimental procedure developed in this study, which affected the physicochemical features of the products.

Synthesis of bis-spiro cyclopropanes based on Meldrum's acid by milling

Reaction of 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum's acid) with various solid aldehydes in the presence of cyanogen bromide and solid sodium ethoxide (EtONa) leads to the selective and efficient formation of bis-spiro cyclopropanes based on Meldrum's acid at the range of 0 °C to room temperature. The products were obtained in good to excellent yields. Structure elucidation is carried out by 1H NMR, 13C NMR, FT-IR spectroscopy, mass analyses and X-ray crystallography techniques. A possible mechanism for the formation of products is also discussed under solvent-free condition.