872310-21-9

Basic information

• Product Name: 1-Propanone, 2-methyl-1-(3-methyl-2-oxiranyl)-
• Synonyms: 1-Propanone, 2-methyl-1-(3-methyl-2-oxiranyl)-
• CAS NO: 872310-21-9
• Molecular Formula: C7H12O2
• Molecular Weight: 128.17
• Mol File: 872310-21-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Propanone, 2-methyl-1-(3-methyl-2-oxiranyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2-methyl-1-(3-methyl-2-oxiranyl)-(872310-21-9)
• EPA Substance Registry System: 1-Propanone, 2-methyl-1-(3-methyl-2-oxiranyl)-(872310-21-9)

Safety Data

• Hazardous Substances Data: 872310-21-9(Hazardous Substances Data)

Upstream product

• 874007-89-3 2-methacryloyl-3-methyl-oxirane 
• 53252-19-0 2-methyl-hex-4-en-3-one 

Relevant articles and documents

The cinchona primary amine-catalyzed asymmetric epoxidation and hydroperoxidation of α,β-unsaturated carbonyl compounds with hydrogen peroxide

Using cinchona alkaloid-derived primary amines as catalysts and aqueous hydrogen peroxide as the oxidant, we have developed highly enantioselective Weitz-Scheffer-type epoxidation and hydroperoxidation reactions of α,β-unsaturated carbonyl compounds (up to 99.5:0.5 er). In this article, we present our full studies on this family of reactions, employing acyclic enones, 5-15-membered cyclic enones, and α-branched enals as substrates. In addition to an expanded scope, synthetic applications of the products are presented. We also report detailed mechanistic investigations of the catalytic intermediates, structure-activity relationships of the cinchona amine catalyst, and rationalization of the absolute stereoselectivity by NMR spectroscopic studies and DFT calculations.