872462-93-6Relevant articles and documents
HIV INTEGRASE INHIBITORS
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, (2010/01/12)
Tricyclic compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein G, T, R1, R2, R3A, R3B, R4A, R4B, R5A, R5B, R6A and R6B are defined herein. The compounds are useful for the prophylaxis or treatment of infection by HIV and the prophylaxis, treatment, or delay in the onset or progression of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se (or as hydrates or solvates thereof) or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
HYDROXYPYRIDINONE DERIVATIVES, THEIR METAL COMPLEXES AND THEIR USE IN THE PRODUCTION OF CONJUGATES WITH BIOMOLECULES
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Page/Page column 70, (2008/06/13)
The invention relates to hydroxypyridinone derivatives, their metal complexes and their use in the production of conjugates with biomolecules. The inventive conjugates are suitable as contrast media in NMR diagnostics. A specific configuration of the liga
Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis
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Page/Page column 26, (2010/11/25)
The invention relates to conjugates of hydroxypyridinone derivative metal complexes and to their preparation. The conjugates are suitable as contrast agents in NMR diagnosis. A high relaxivity is achieved and the NMRD maximum is raised through a specific