872973-88-1

Basic information

• Product Name: 1,6-Naphthyridine-2,5,7(1H,6H,8H)-trione, 1-(2,6-dichlorophenyl)-6-[(4-methoxyphenyl)methyl]-
• CAS NO: 872973-88-1
• Molecular Formula: C22H16Cl2N2O4
• Molecular Weight: 443.286
• Mol File: 872973-88-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,6-Naphthyridine-2,5,7(1H,6H,8H)-trione, 1-(2,6-dichlorophenyl)-6-[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-Naphthyridine-2,5,7(1H,6H,8H)-trione, 1-(2,6-dichlorophenyl)-6-[(4-methoxyphenyl)methyl]-(872973-88-1)
• EPA Substance Registry System: 1,6-Naphthyridine-2,5,7(1H,6H,8H)-trione, 1-(2,6-dichlorophenyl)-6-[(4-methoxyphenyl)methyl]-(872973-88-1)

Safety Data

• Hazardous Substances Data: 872973-88-1(Hazardous Substances Data)

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 872973-83-6 4-[(2,6-dichlorophenyl)amino]-1-(4-methoxybenzyl)pyridine-2,6-(1H,3H)-dione 
• 5941-55-9 ethyl 3-ethoxyacrylate 
• 922-67-8 propynoic acid methyl ester 

Downstream Products

• 872973-93-8 7-chloro-1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-1,6-naphthyridin-2-(1H)-one 
• 872973-91-6 1-(2,6-dichlorophenyl)-7-hydroxy-1,6-naphthyridine-2,5-(1H,6H)-dione 
• 872973-92-7 5,7-dichloro-1-(2,6-dichlorophenyl)-1,6-naphthyridin-2-(1H)-one 

Relevant articles and documents

Efficient synthesis of a trisubstituted 1,6-naphthyridone from acetonedicarboxylate and regioselective Suzuki arylation

An efficient five-step synthesis of 1,6-naphthyridone 3b, a p38 mitogen-activated protein (MAP) kinase inhibitor intermediate, in 32% overall yield starting from acetonedicarboxylate (ADC) is described. The synthesis began with a selective monoamidation o