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87304-15-2

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87304-15-2 Usage

Description

(2S)-2-[[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid is a complex organic compound belonging to the peptide class. It is a derivative of the amino acid leucine, featuring multiple functional groups such as amino acids, hydroxyl, and phenyl groups. (2S)-2-[[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid is characterized by its stereochemistry, with the (2S) and (2S,3R) notations indicating the specific spatial arrangement of its atoms.

Uses

Used in Biochemistry and Pharmacology Research:
(2S)-2-[[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid is utilized as a reference standard in biochemical and pharmacological research. Its well-defined structure and functional groups make it a valuable tool for understanding the interactions between peptides and biological systems.
Used in Synthesis of Peptides and Pharmaceuticals:
(2S)-2-[[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid serves as a building block for the synthesis of peptides and pharmaceuticals. Its unique structure allows it to be incorporated into larger molecules with specific biological activities, potentially leading to the development of new drugs and therapeutic agents.
Used in Therapeutic Applications:
Due to its interactions with biological systems and enzymes, (2S)-2-[[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid may have potential therapeutic applications. Its complex structure and functional groups could contribute to its efficacy in treating various diseases or conditions, although further research is needed to explore these possibilities.

Check Digit Verification of cas no

The CAS Registry Mumber 87304-15-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,3,0 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 87304-15:
(7*8)+(6*7)+(5*3)+(4*0)+(3*4)+(2*1)+(1*5)=132
132 % 10 = 2
So 87304-15-2 is a valid CAS Registry Number.

87304-15-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Boc bestatin

1.2 Other means of identification

Product number -
Other names (S)-2-[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:87304-15-2 SDS

87304-15-2Relevant articles and documents

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Hou, Xiaohan,Jia, Geng,Jiang, Yuqi,Li, Peixia,Li, Xiaoyang,Tan, Leqiao,Wang, Xuejian,Xu, Wenfang,Yue, Kairui,Zhang, Jian,Zhang, Liang,Zhang, Zhaolin

, (2021/09/22)

In our previous study, we discovered a ubenimex-fluorouracil (5FU) conjugates BC-02, which displays significant in vivo anti-tumor activity, however, the instability of BC-02 in plasma limits its further development as a drug candidate. Herein, we designe

TUBULIN BINDING AGENTS

-

Paragraph 1083; 1084; 1085; 1086; 1087, (2015/02/18)

The invention provides combretastatin A-4 like compounds that are modified to have enhanced tubulin binding activity and in some embodiments the ability to promote accumulation in the vasculature undergoing angiogenesis (homing activity). The compounds are based on the combretastatin A-4 skeletal structure having a tubulin-binding pharmacophore comprising two fused rings (A and B rings) in which the B ring is substituted with (a) an aromatic ring structure (C ring) and (b) a second substituent/functional group that comes off the B ring. The aromatic ring structure is typically a six membered ring phenolic or aniline structure, or may also be a fused ring structure such as a substituted or unsubstituted naphthalene. The second substituent on the B ring may for example be a substituent which has been found to provide enhanced tubulin binding activity (for example a carbonyl group), or may be a substituent that facilitates functionalisation of the B ring (for example an hydroxyl or amine group), or it may be a binding agent for a target that is preferentially expressed on vasculature undergoing angiogenesis, and not expressed on quiescent vasculature.

Development of target protein-selective degradation inducer for protein knockdown

Itoh, Yukihiro,Ishikawa, Minoru,Kitaguchi, Risa,Sato, Shinichi,Naito, Mikihiko,Hashimoto, Yuichi

experimental part, p. 3229 - 3241 (2011/06/25)

Our previous technique for inducing selective degradation of target proteins with ester-type SNIPER (Specific and Nongenetic Inhibitor-of-apoptosis- proteins (IAPs)-dependent Protein ERaser) degrades both the target proteins and IAPs. Here, we designed a

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