87310-65-4Relevant articles and documents
SELECTIVE ESTROGEN RECEPTOR MODULATOR
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Page/Page column 48; 49; 50, (2010/04/27)
The present invention is directed to a compound of the formula (A): or a pharmaceutically acceptable salt thereof; and also to compounds of formula (I): or a pharmaceutically acceptable salt thereof.
ETHER DERIVATIVES HAVING 5-LIPOXYGENASE INHIBITORY ACTIVITY
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, (2008/06/13)
The invention concerns ether derivatives of the formula I Q1?X?Ar?Q2 wherein Q1 is an optionally substituted 9-, 10- or 11-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur; X is oxy, thio, sulphinyl or sulphonyl; Ar is optionally substituted phenylene, pyridinediyl, pyrimidinediyl, thiophenediyl, furandiyl, thiazolediyl, oxazoiediyl, thiadiazoiediyl or oxadiazolediyl; and Q2 is selected from the groups of the formulae II and III: wherein R1 is hydrogen, (2-5C)alkanoyl or optionally substituted benzoyl; R2 is (l-4C)alkyl; and R3 is hydrogen or (l-4C)alkyl; or R2 and R3 are linked to form a methylene, vinylene, ethylene or trimethylene group; or a pharmaceutically-acceptable salt thereof; processes for their preparation; pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors.
Acetanilide derivatives
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, (2008/06/13)
The invention concerns acetanilide derivatives of the formula I wherein R4 is (1-4C)alkyl; R5 is hydrogen or (1-4C)alkyl; Ar1 is phenylene, pyridinediyl or pyrimidinediyl; A1 is a direct link to X1 or A1 is (1-4C)alkylene; X1 is oxy, thio, sulphinyl or su
