873192-82-6

Basic information

• Product Name: 1H-Pyrrole-3-carboxylic acid, 2-[[[(2-chloroethyl)amino]carbonyl]amino]-5-(4-methylphenyl)-, ethyl ester
• CAS NO: 873192-82-6
• Molecular Formula: C17H20ClN3O3
• Molecular Weight: 349.817
• Mol File: 873192-82-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carboxylic acid, 2-[[[(2-chloroethyl)amino]carbonyl]amino]-5-(4-methylphenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxylic acid, 2-[[[(2-chloroethyl)amino]carbonyl]amino]-5-(4-methylphenyl)-, ethyl ester(873192-82-6)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxylic acid, 2-[[[(2-chloroethyl)amino]carbonyl]amino]-5-(4-methylphenyl)-, ethyl ester(873192-82-6)

Safety Data

• Hazardous Substances Data: 873192-82-6(Hazardous Substances Data)

Upstream product

• 50551-10-5 ethyl amidinoacetate 
• 2318-25-4 ethyl 3-ethoxy-3-iminopropanoate hydrochloride 
• 873192-77-9 2-amino-5-(4-methylphenyl)-1H-pyrrole-3-carboxylic acid ethyl ester 
• 1943-83-5 2-chloroethyl isothiocyanate 

Relevant articles and documents

3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high-affinity and selective α1- adrenoceptor ligands

The discovery of a new series of selective and high-affinity α1-adrenoceptor (α1-AR) ligands, characterized by a 1H-pyrrolo[2,3-d]-pyrimidine-2,4(3H,7H)-dione system, is described in this paper. Some synthesized compounds, including 20, 22, and 30, displayed affinity in the nanomolar range for α1-ARs and substantial selectivity with respect to 5-HT1A and dopaminergic D1 and D 2 receptors. Functional assays, performed on selected derivatives, showed antagonistic properties.