873200-46-5

Basic information

• Product Name: L-Aspartic acid, N-(2-bromoethyl)-N-[2-(1,1-dimethylethoxy)-2-oxoethyl]-, 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester
• CAS NO: 873200-46-5
• Molecular Formula: C23H34BrNO6
• Molecular Weight: 500.43
• Mol File: 873200-46-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: L-Aspartic acid, N-(2-bromoethyl)-N-[2-(1,1-dimethylethoxy)-2-oxoethyl]-, 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Aspartic acid, N-(2-bromoethyl)-N-[2-(1,1-dimethylethoxy)-2-oxoethyl]-, 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester(873200-46-5)
• EPA Substance Registry System: L-Aspartic acid, N-(2-bromoethyl)-N-[2-(1,1-dimethylethoxy)-2-oxoethyl]-, 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester(873200-46-5)

Safety Data

• Hazardous Substances Data: 873200-46-5(Hazardous Substances Data)

Upstream product

• 2177-63-1 (S)-2-amino-4-(benzyloxy)-4-oxobutanoic acid 
• 873200-45-4 N-(tert-butyloxycarbonylmethyl)-L-aspartic acid-β-benzyl-α-tert-butyl ester 
• 103935-47-3 2-bromoethyl triflate 

Relevant articles and documents

Polyhydroxylated GdDTPA-derivatives as high relaxivity magnetic resonance imaging contrast agents

The search for new MRI agents endowed with high relaxivity at the magnetic field strength of clinical scanners (1.5-3 T) is still receiving great attention from researchers involved in the development of new probes. Such Gd(iii) complexes should combine a

CONTRAST AGENTS ENDOWED WITH HIGH RELAXIVITY

The present invention relates to a novel class of paramagnetic ion-based contrast agents of formula (I), wherein a chelating backbone moiety is highly functionalized by the presence of one or more polyhdroxylated chain, that show a pharmacokinetic profile analogous to that of the commonly used T1-general extravascular agents (NSA) but are further characterized by a higher relaxivity.