873208-18-5Relevant articles and documents
S,O-Ligand-Promoted Pd-Catalyzed C–H Olefination of Thiophenes
álvarez-Casao, Yolanda,Fernández-Ibá?ez, M. ángeles
supporting information, p. 1842 - 1845 (2019/02/25)
An efficient PdII catalyzed C–H olefination of thiophenes has been developed using an easily accessible bidentate S,O-ligand. The catalytic system promotes the C-2 olefination of a wide range of thiophenes bearing both, electron donating and wi
A robust first-pass protocol for the heck-mizoroki reaction
Murray, Paul M.,Bower, John F,Cox, David K,Galbraith, Ewan K,Parker, Jeremy S,Sweeney, Joseph B.
, p. 397 - 405 (2013/04/24)
The Heck-Mizoroki (HM) reaction is one of the most widely used C-C bond-forming methods of contemporary synthesis. Notwithstanding this, these reactions frequently require significant optimization before efficient transformations can be obtained. We describe here the results of a study that aimed to establish a generic experimental protocol for HM reactions which enables acceptable yields from first-pass experiments. The methodology utilizes readily available stable catalysts and can be applied to a broad range of coupling partners.