873437-13-9 Usage
Description
(3-Hydroxy-propyl)-isopropyl-carbamic acid tert-butyl ester, commonly known as isocarbophos, is a carbamate insecticide and acaricide with the chemical formula C10H21NO4. It is a colorless to pale yellow liquid with a slight odor and is soluble in water. Isocarbophos works by inhibiting cholinesterase activity in target organisms, leading to paralysis and death.
Uses
Used in Pesticide Industry:
Isocarbophos is used as an insecticide and acaricide for the control of various pests, including mites, caterpillars, and moths. It is effective against a wide range of pests and is commonly used on crops such as vegetables, fruits, and ornamental plants.
Used in Acaricide Industry:
Isocarbophos is also used as an acaricide to control mite populations in agricultural settings. Its ability to inhibit cholinesterase activity makes it effective in managing mite infestations and protecting crops from damage.
However, it is important to note that isocarbophos is toxic to non-target organisms and can pose a risk to human and environmental health. Therefore, it should be used with caution and in accordance with safety guidelines and regulations to minimize potential harm.
Check Digit Verification of cas no
The CAS Registry Mumber 873437-13-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,3,4,3 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 873437-13:
(8*8)+(7*7)+(6*3)+(5*4)+(4*3)+(3*7)+(2*1)+(1*3)=189
189 % 10 = 9
So 873437-13-9 is a valid CAS Registry Number.
873437-13-9Relevant articles and documents
IRAK DEGRADERS AND USES THEREOF
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Paragraph 00962; 001925; 001928; 001929, (2020/06/19)
The present invention provides compounds, compositions thereof, and methods of using the same.
Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90
He, Huazhong,Zatorska, Danuta,Kim, Joungnam,Aguirre, Julia,Llauger, Laura,She, Yuhong,Wu, Nian,Immormino, Robert M.,Gewirth, Daniel T.,Chiosis, Gabriela
, p. 381 - 390 (2007/10/03)
Hsp90 is a chaperone protein that allows cancer cells to tolerate the many components of dysregulated pathways. Its inactivation may result in targeting multiple molecular alterations and, thus, in reverting the transformed phenotype. The PU-class, a purine-scaffold Hsp90 inhibitor series, has been reported to be potent and selective against Hsp90 both in vitro and in vivo models of cancer. Here, a series of this class was synthesized and evaluated as inhibitors of the chaperone. The structure-activity relationship and selectivity for tumor Hsp90 of compounds within the series is presented. The study identifies water soluble derivatives (> 5 mM in PBS pH 7.4) of nanomolar potency (IC50 ～ 50 nM) in cellular and animal models of cancer. Binding affinities of these compounds for Hsp90 correlate well with their biological activities. When administered in vivo to mice bearing MDA-MB-468 human breast cancer xenografted tumors, these agents result in pharmacologically relevant concentrations and, accordingly, in modulation of Hsp90-client proteins in tumors.
