87355-48-4

Basic information

• Product Name: all-E-(20-⁽¹³⁾C)retinal
• CAS NO: 87355-48-4
• Molecular Weight: 285.431
• Mol File: 87355-48-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: all-E-(20-⁽¹³⁾C)retinal(CAS DataBase Reference)
• NIST Chemistry Reference: all-E-(20-⁽¹³⁾C)retinal(87355-48-4)
• EPA Substance Registry System: all-E-(20-⁽¹³⁾C)retinal(87355-48-4)

Safety Data

• Hazardous Substances Data: 87355-48-4(Hazardous Substances Data)

Upstream product

• 141207-99-0 N-methoxy-N,5-dimethyl-7-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6-heptanetrienamide 
• 87374-26-3 (E)-1-13C-6-methyl-8-(2,6,6-trimethyl-1-cyclohexenyl)-3,5,7-octatrien-2-one 
• 3917-41-7 (2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal 
• 87355-44-0 (E)-1-13C-6-methyl-8-(2,6,6-trimethyl-1-cyclohexenyl)-3,5,7-octatrien-2-ol 
• 6980-79-6 (2E,4E,6E)-5-methyl-7-(2’,6’,6’-trimethylcyclohex-1’-en-1’-yl)-hepta-2,4,6-trienenal 
• 5560-99-6 (2X,4E)-3-methyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-penta-2,4-dienal 
• 73198-78-4 α-(Trimethylsilyl)-tert-butylacetaldimine 

Relevant articles and documents

Synthesis of (12,13-(13)C2)retinal and (13,14-(13)C2)retinal: a strategy to prepare multiple-(13)C-labeled conjugated systems

(12,13-(13)C2)Retinal, (13,14-(13)C2)retinal, (19-(13)C)retinal and (20-(13)C)retinal (1) were prepared in a simple fashion in high yield via a consecutive strategy.The key step is the reaction of a N-methoxy-N-methylamide with an alkyllithium or a Grignard reagent.The preparation of the required N-methoxy-N-methylamide is discussed.In this scheme, only three commercially available (13)C-labeled starting materials (ethyl bromoacetate, acetonitrile and methyl iodide) are sufficient to construct retinals with any possible combination of (13)C labeling in the conjugated tail end.This strategy is applicable to the preparation of many other conjugated systems, such as retinoids, carotenoids and polyenes.