87363-81-3

Basic information

• Product Name: ^tBOC-Gly-ΔPhe-(S)-Met-OMe
• Synonyms: ^tBOC-Gly-ΔPhe-(S)-Met-OMe
• CAS NO: 87363-81-3
• Molecular Weight: 465.571
• Mol File: 87363-81-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ^tBOC-Gly-ΔPhe-(S)-Met-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: ^tBOC-Gly-ΔPhe-(S)-Met-OMe(87363-81-3)
• EPA Substance Registry System: ^tBOC-Gly-ΔPhe-(S)-Met-OMe(87363-81-3)

Safety Data

• Hazardous Substances Data: 87363-81-3(Hazardous Substances Data)

Upstream product

• 89093-60-7 2-(2-tert-Butoxycarbonylamino-acetylamino)-3-hydroxy-3-phenyl-propionic acid ethyl ester 
• 147781-99-5 Boc-Gly-DL-Phe(β-OH)-OH 
• 42267-16-3 (d,l)-phenylserine ethyl ester hydrochloride 
• 4530-20-5 BOC-glycine 
• 2491-18-1 (S)-methyl 2-amino-4-(methylthio)butanoate hydrochloride 
• 124194-31-6 Boc-Gly-Δ^ZPhe azlactone 
• 10332-17-9 Met-OMe 
• 74805-42-8 N-carboxy-α-dehydrophenylalanine anhydride 
• 83791-32-6 N-carboxy dehydrophenylalanine anhydride 

Downstream Products

• 69872-63-5 N-(tert-butyloxycarbonyl)glycyl-L-phenylalanyl-L-methionine methyl ester 
• 93200-06-7 (S)-2-[(R)-2-(2-tert-Butoxycarbonylamino-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid methyl ester 

Relevant articles and documents

Dehydrooligopeptides. VII. Convenient Synthesis of Various Dehydrodi- and tripeptide Esters by Using N-Carboxy α-Dehydroamino Acid Anhydride

The one-pot syntheses of N-protected Δ1- and Δ2-dehydrodipeptide esters by the coupling of N-carboxy α-dehydroamino acid anhydride (ΔNCA) with several kinds of C- or N-protected L-α-amino acids are described.In addition, it was found that a similar coupling of ΔNCA with both C- and N-protected α-amino acids also took place to give Δ2-dehydrotripeptide derivatives, involving eight kinds of important C-terminal segments of antrimycins and cirratiomycins.The configurational confirmation of the α-dehydroisoleucine residue of the antibiotics is also discussed.

FACILE AND USEFUL ONE-POT SYNTHESIS OF DEHYDROOLIGOPEPTIDES USING ΔNCA

One-pot coupling of ΔNCA with N- and C-terminus α-amino acid, peptide, or dehydropeptide was achieved to give various types of dehydrooligopeptides.