87378-59-4 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
A pyridinium derivative is a compound that contains a pyridine ring, which is a six-membered aromatic ring with one nitrogen atom.
Explanation
A pyrimidine ring is a six-membered heterocyclic ring with four carbon atoms and two nitrogen atoms.
Explanation
A ketone functional group is a carbonyl group (C=O) bonded to two carbon atoms. In this compound, the ketone group is part of the 4-oxo-2,6-bis(trifluoromethyl)-4,5-dihydropyrimidin-5-yl moiety.
Explanation
The compound is utilized in the synthesis of various biologically active compounds, making it a valuable building block in the development of new pharmaceuticals.
Explanation
The compound serves as a reagent in organic synthesis, which is the chemical synthesis of organic compounds.
Explanation
The compound acts as a precursor, or starting material, for the synthesis of heterocyclic compounds, which are organic compounds containing a ring of atoms with at least one heteroatom (an atom other than carbon).
Explanation
The compound's unique structure and reactivity make it a crucial intermediate in the synthesis of various pharmaceuticals and other useful organic compounds.
Pyridinium derivative
Contains a pyridine ring
Pyrimidine ring
Part of the compound's structure
Two trifluoromethyl groups
Attached to the pyrimidine ring
Ketone functional group
Present in the molecule
Pharmaceutical research and development
Used as a building block
Organic synthesis
Utilized as a reagent
Precursor for heterocyclic compounds
Used in the preparation of heterocyclic compounds
Unique structure and reactivity
Important intermediate in the production of pharmaceuticals and organic compounds
Check Digit Verification of cas no
The CAS Registry Mumber 87378-59-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,3,7 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87378-59:
(7*8)+(6*7)+(5*3)+(4*7)+(3*8)+(2*5)+(1*9)=184
184 % 10 = 4
So 87378-59-4 is a valid CAS Registry Number.
87378-59-4Relevant articles and documents
Fluorocarbon Derivatives of Nitrogen. Part 13. Reaction of Perfluoroalkanenitriles with Pyridinium Alkoxycarbonylmethylides: Synthesis of Perfluoroalkylated Imidazopyridines (1-Azaindolizines). X-Ray Molecular Structure of Pyridinium 4,5-Dihydro-4-oxo-2,6-bis(trifluoromethyl)py...
Banks, Ronald E.,Pritchard, Robin G.,Thomson, Julie
, p. 1769 - 1776 (2007/10/02)
Pyridinium t-butoxycarbonylmethylide, generated in situ by treatment of N-(t-butoxycarbonylmethyl)pyridinium perchlorate with sodium hydride (in acetonitrile) or triethylamine (in dichloromethane), reacts with trifluoroacetonitrile to yield 3-(t-butoxycarbonyl)-2-(trifluoromethyl)imidazopyridine, N-pyridinium perchlorate, and pyridinium 4,5-dihydro-4-oxo-2,6-bis(trifluoromethyl)pyrimidin-5-ylide.The corresponding heptafluoropropyl compounds can be prepared in the same way, starting from heptafluorobutyronitrile; in both cases, the relative yields of the three types of product can be varied by changing the reactant ratios.Treatment of N-pyridinium perchloroate with heptafluorobutyronitrile in the presence of triethylamine gives 2-(heptafluoropropyl)-4,5-dihydro-4-oxo-6-(trifluoromethyl)pyrimidin-5-ylide.Trapping of pyridinium ethoxycarbonylmethylide with trifluoroacetonitrile provides the known 3-(ethoxycarbonyl)-2-(trifluoromethyl)imidazopyridine, plus pyridinium 4,5-dihydro-4-oxo-2,6-bistrifluoromethyl)pyrimidin-5-ylide.Reduction (zinc-acetic acid) of the latter, for which a detailed X-ray crystallographic analysis has been performed, gave 4-hydroxy-2,6-bis(trifluoromethyl)pyrimidine.A stepwise mechanism is proposed to account for the cycloaddition step involved in formation of perfluoroalkylated imidazopyridines form pyridinium alkoxycarbonylmethylides and the perfluoroalkanenitriles CF3CN and n-C3F7CN.
