874096-44-3Relevant articles and documents
Peptide-bond modified glutathione conjugate analogs modulate GSTπ function in GSH-conjugation, drug sensitivity and JNK signaling
Burg, Danny,Riepsaame, Joey,Pont, Chantal,Mulder, Gerard,Van De Water, Bob
, p. 268 - 277 (2007/10/03)
Glutathione S-transferase π (GST, E.C.2.5.1.18) overexpression contributes to resistance of cancer cells towards cytostatic drugs. Furthermore, GSTπ is involved in the cellular stress response through inhibition of Jun N-terminal-kinase (JNK), a process t