874297-80-0 Usage
General Description
1-CYCLOPENTYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA is a chemical compound that belongs to the class of urea derivatives. It has a cyclopentyl group attached to the urea moiety, and a phenyl ring with a dioxaborolane group as a substituent. 1-CYCLOPENTYL-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]UREA has potential applications in medicinal chemistry, as urea derivatives have been studied for their biological activities such as antitumor, antifungal, and antiviral properties. The presence of the dioxaborolane group also makes this compound interesting for potential use in organic synthesis and as a building block for other chemical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 874297-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,2,9 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 874297-80:
(8*8)+(7*7)+(6*4)+(5*2)+(4*9)+(3*7)+(2*8)+(1*0)=220
220 % 10 = 0
So 874297-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H27BN2O3/c1-17(2)18(3,4)24-19(23-17)13-9-11-15(12-10-13)21-16(22)20-14-7-5-6-8-14/h9-12,14H,5-8H2,1-4H3,(H2,20,21,22)
874297-80-0Relevant articles and documents
Thienopyridine urea inhibitors of KDR kinase
Heyman, H. Robin,Frey, Robin R.,Bousquet, Peter F.,Cunha, George A.,Moskey, Maria D.,Ahmed, Asma A.,Soni, Niru B.,Marcotte, Patrick A.,Pease, Lori J.,Glaser, Keith B.,Yates, Melinda,Bouska, Jennifer J.,Albert, Daniel H.,Black-Schaefer, Candace L.,Dandliker, Peter J.,Stewart, Kent D.,Rafferty, Paul,Davidsen, Steven K.,Michaelides, Michael R.,Curtin, Michael L.
, p. 1246 - 1249 (2007/10/03)
A series of substituted thienopyridine ureas was prepared and evaluated for enzymatic and cellular inhibition of KDR kinase activity. Several of these analogs, such as 2, are potent inhibitors of KDR (10 nM) in both enzymatic and cellular assays. Further
