874479-16-0 Usage
General Description
(Z)-3-chloro-3-(4-methoxyphenyl)acrylonitrile, also known as 4-(4'-Methoxyphenyl)-3-chloroacrylonitrile, is a chemical compound with the molecular formula C10H8ClNO. It is a highly reactive compound that is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is a clear, colorless to pale yellow liquid with a sharp, pungent odor. (Z)-3-chloro-3-(4-methoxyphenyl)acrylonitrile is known to be a strong irritant to the skin, eyes, and respiratory system and should be handled with care in a laboratory or industrial setting. Additionally, it is classified as a potential mutagen and may have harmful effects on aquatic organisms, making it important to use appropriate safety and environmental precautions when working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 874479-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,4,7 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 874479-16:
(8*8)+(7*7)+(6*4)+(5*4)+(4*7)+(3*9)+(2*1)+(1*6)=220
220 % 10 = 0
So 874479-16-0 is a valid CAS Registry Number.
874479-16-0Relevant articles and documents
Synthesis of thiophene analogues of the tacrine series
Thomae, David,Kirsch, Gilbert,Seck, Pierre
, p. 1027 - 1032 (2008/02/02)
3-Amino-2-cyanothiophenes condensed with cyclanones and afforded analogues of Velnacrine in two or three steps. Condensation under Friedlander's conditions gave tacrine analogues in one step. Georg Thieme Verlag Stuttgart.
Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B
Andersen, Henrik Sune,Olsen, Ole H.,Iversen, Lars F.,S?rensen, Anette L. P.,Mortensen, Steen B.,Christensen, Michael S.,Branner, Sven,Hansen, Thomas K.,Lau, Jesper F.,Jeppesen, Lone,Moran, Edmond J.,Su, Jing,Bakir, Farid,Judge, Luke,Shahbaz, Manou,Collins, Tassie,Vo, Todd,Newman, Michael J.,Ripka, William C.,M?ller, Niels Peter H.
, p. 4443 - 4459 (2007/10/03)
Reversible phosphorylation and dephosphorylation of key proteins on tyrosine residues are important parts of intracellular signaling triggered by hormones and other agents. Recent knock-out studies in mice have identified PTP1B as a potential target for t
