874758-84-6 Usage
General Description
2-Chloro-4-pyrrolidin-1-yl-pyridine is a chemical compound that consists of a pyrrolidinyl-pyridine structure with a chlorine atom attached at the 2-position. It is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs and active pharmaceutical ingredients. Its unique chemical structure makes it a valuable building block for the development of potential drug candidates and it has shown promise in the treatment of various medical conditions. Additionally, it has been studied for its potential antitumor and antiviral properties, making it an important target for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 874758-84-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,7,5 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 874758-84:
(8*8)+(7*7)+(6*4)+(5*7)+(4*5)+(3*8)+(2*8)+(1*4)=236
236 % 10 = 6
So 874758-84-6 is a valid CAS Registry Number.
874758-84-6Relevant articles and documents
Preparative-Scale Synthesis of Vedejs Chiral DMAP Catalysts
Kinens, Artis,Balkaitis, Simonas,Suna, Edgars
, p. 12449 - 12459 (2018/10/20)
A scalable synthesis of chiral Vedejs-type DMAP catalysts is reported. The key step of the synthesis is amination of the enantiomerically pure 4-chloropyridine derivative using well-defined ZnCl2(amine)2 complexes. A series of Zn(II)-amine complexes have been synthesized to explore the scope of the ZnCl2-mediated amination of 4-halopyridines. Mechanistic studies support a Zn(II)-facilitated nucleophilic aromatic substitution as a plausible mechanism for the chlorine-to-amine exchange.
