874983-88-7

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 8-methoxy-3-[[[3-methyl-5-(2-phenylethenyl)-4-isoxazolyl]amino]acetyl]-
• CAS NO: 874983-88-7
• Molecular Formula: C24H20N2O5
• Molecular Weight: 416.433
• Mol File: 874983-88-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 8-methoxy-3-[[[3-methyl-5-(2-phenylethenyl)-4-isoxazolyl]amino]acetyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 8-methoxy-3-[[[3-methyl-5-(2-phenylethenyl)-4-isoxazolyl]amino]acetyl]-(874983-88-7)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 8-methoxy-3-[[[3-methyl-5-(2-phenylethenyl)-4-isoxazolyl]amino]acetyl]-(874983-88-7)

Safety Data

• Hazardous Substances Data: 874983-88-7(Hazardous Substances Data)

Upstream product

• 53558-01-3 4-amino-3-methyl-5-styryl isoxazole 
• 106578-18-1 3-(2-bromoacetyl)-8-methoxy-2H-chromen-2-one 

Downstream Products

• 874983-97-8 3-[2-mercapto-1-(3-methyl-5-styryl-isoxazol-4-yl)-1H-imidazol-4-yl]-8-methoxy-chromen-2-one 

Relevant articles and documents

Synthesis of imidazole, coumarin and isoxazole containing new triheterocyclic compounds and their derivatives

Reaction of substituted 4-amino-3-methyl-5-styrylisoxazoles 1 with 3-(2-bromoacetyl)coumarin 2 in abs. ethanol leads to the formation of 3-[2-(3-methyl-5-styryl-4-ylamino)acetyl]chromen-2-ones 3, which are subsequently cyclised by treatment with KSCN to 3-[1-(3-methyl-5-styryl- isoxazol-4-yl)-2-mercapto-1H-imidazol-4-yl]-1-benzopyran-2H-ones 4, 2-Mercaptoimidazoles 4 on treatment with ClCH2COCl in DMF/abs. ethanol give unexpected product esters 5. The reaction of 4 with phenacyl bromides results in the formation of thioethers 6.