875-41-2

Basic information

• Product Name: 5,6-diamino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• CAS NO: 875-41-2
• Molecular Formula: C₅H₈N₄OS
• Molecular Weight: 172.2082
• Mol File: 875-41-2.mol
• Article Data: 3

Chemical Properties

• Density: 1.55g/cm³
• Refractive Index: 1.741
• CAS DataBase Reference: 5,6-diamino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-diamino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one(875-41-2)
• EPA Substance Registry System: 5,6-diamino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one(875-41-2)

Safety Data

• Hazardous Substances Data: 875-41-2(Hazardous Substances Data)

Upstream product

• 16837-08-4 6-amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 
• 54030-50-1 6-amino-1-methyl-5-nitroso-2-thiouracil 
• 54030-50-1 6-amino-2-mercapto-1-methyl-5-nitrosopyrimidin-4(1H)-one 

Downstream Products

• 141859-29-2 6-Amino-1-methyl-2-thioxo-5-{[1-p-tolyl-meth-(E)-ylidene]-amino}-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-35-0 6-Amino-5-{[1-(4-fluoro-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-26-9 6-Amino-5-{[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-25-8 6-Amino-5-{[1-(2-chloro-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-28-1 6-Amino-1-methyl-5-{[1-(4-nitro-phenyl)-meth-(E)-ylidene]-amino}-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-24-7 6-Amino-1-methyl-5-{[1-phenyl-meth-(E)-ylidene]-amino}-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-30-5 6-Amino-5-{[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-27-0 6-Amino-5-{[1-(4-bromo-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 141859-33-8 6-Amino-5-{[1-(2-fluoro-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 28139-02-8 2‐mercapto‐3‐methylhypoxanthine 
• 141859-31-6 6-Amino-5-{[1-(4-dimethylamino-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 103258-00-0 3-methyl-8-phenyl-2-thioxanthine 
• 141859-34-9 6-Amino-5-{[1-(3-fluoro-phenyl)-meth-(E)-ylidene]-amino}-1-methyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 103256-02-6 2-phenyl-4-methyl-s-triazolo<4,3-a>purin-9(4H)-one 

Relevant articles and documents

Synthesis and evaluation of antitumour activities of novel fused tri-And tetracyclic uracil derivatives

Simple one-pot syntheses of indenopyrrolopyrimidines and indolopyrrolopyrimidines were achieved via the cyclocondensation of 6-Aminouracils and, respectively, ninhydrin and isatin in the presence of catalytic amounts of glacial acetic acid. Similarly, 5,6-diaminouracil derivatives were used as starting materials for the synthesis of indenopteridines and indolopteridines via their reaction with ninhydrin and isatin, respectively. The synthesised compounds were evaluated for antitumour activity against a human hepatocellular carcinoma cell line (HepG2), some showing antitumour activity comparable with 5-fluorouracil and imatinib.

Isolation, synthesis, and biological activity of aphrocallistin, an adenine-substituted bromotyramine metabolite from the hexactinellida sponge Aphrocallistes beatrix

A new adenine-substituted bromotyrosine-derived metabolite designated as aphrocallistin (1) has been isolated from the deep-water Hexactinellida sponge Aphrocallistes beatrix. Its structure was elucidated on the basis of spectral data and confirmed throug