87504-16-3

Basic information

• Product Name: 2-methyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one
• CAS NO: 87504-16-3
• Molecular Weight: 205.24
• Mol File: 87504-16-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-methyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one(87504-16-3)
• EPA Substance Registry System: 2-methyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one(87504-16-3)

Safety Data

• Hazardous Substances Data: 87504-16-3(Hazardous Substances Data)

Upstream product

• 87504-23-2 2-Thioxo-2,3-dihydro-benzoimidazole-1-carboxylic acid methylamide 

Relevant articles and documents

Process for scavenging thiols

Thiols are trapped, and converted to disulfide compounds, by a process of reacting them with compounds containing a 1,2,4-thiadiazole ring structure carrying a substituent at position 3 of the thiadiazole ring, and being unsubstituted at position N-2. The process is useful pharmacologically, in inhibiting certain thiol-containing enzymes such as H+/K+-ATPase (the proton pump), and industrially, in selective removal of thiol compounds from gas or liquid mixtures.

THIADIAZOLE COMPOUNDS USEFUL AS PROTON PUMP INHIBITORS

Novel thiadiazole compounds are provided, which are effective as proton pumps inhibitors, useful in treating peptic ulcers by inhibition of the proton pump enzyme H+/K+-ATPase. The compounds are 3-substituted 1,2,4-thiadiazolo [4,5-alpha] benzimidazole an