875639-20-6

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 3-(2,2-difluoro-1,3-benzodioxol-4-yl)-1-[(4-methylphenyl)sulfonyl]-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
• CAS NO: 875639-20-6
• Molecular Formula: C27H25BF2N2O6S
• Molecular Weight: 554.379
• Mol File: 875639-20-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 3-(2,2-difluoro-1,3-benzodioxol-4-yl)-1-[(4-methylphenyl)sulfonyl]-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 3-(2,2-difluoro-1,3-benzodioxol-4-yl)-1-[(4-methylphenyl)sulfonyl]-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-(875639-20-6)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 3-(2,2-difluoro-1,3-benzodioxol-4-yl)-1-[(4-methylphenyl)sulfonyl]-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-(875639-20-6)

Safety Data

• Hazardous Substances Data: 875639-20-6(Hazardous Substances Data)

Upstream product

• 126120-87-4 (2,2-difluorobenzo[d][1,3]dioxol-4-yl)boronic acid 
• 1112662-77-7 C₂₁H₁₃BrF₂N₂O₄S 
• 73183-34-3 bis(pinacol)diborane 
• 875639-15-9 5-bromo-3-iodo-1-(4-methylbenzene-1-sulfonyl)-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1613712-88-1 C₂₈H₂₂F₂N₄O₅S₂ 

Relevant articles and documents

SUBSTITUTED 1H-PYRROLO [2,3-B] PYRIDINE AND 1H-PYRAZOLO [3, 4-B] PYRIDINE DERIVATIVES AS SALT INDUCIBLE KINASE 2 (SIK2) INHIBITORS

The present invention relates to compounds according to Formulas I, IA or IB: to pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes.

PYRROLO-PYRIDINE KINASE MODULATORS

The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.