87573-79-3Relevant articles and documents
Syntheses and Reactions of Some 5-Vinyl- and 5-Ethynylpyrimidines
Benneche, Tore,Undheim, Kjell
, p. 235 - 240 (2007/10/02)
5-β,β-Dichlorovinyl- and 5-α-chlorovinylpyrimidines have been prepared from 5-acetyl-2-methylthiopyrimidines.HCl elimination from the 5-α-chlorovinyl derivatives yields the 5-ethynyl analogues.Peracid or chlorine oxidation of the sulfides yields the sulfones which may be hydrolyzed to the corresponding lactams.The reaction paths are discussed.