87586-00-3Relevant articles and documents
Chemoenzymatic synthesis of 3-deoxy-3-fluoro-l-fucose and its enzymatic incorporation into glycoconjugates
Valverde, Pablo,Vendeville, Jean-Baptiste,Hollingsworth, Kristian,Mattey, Ashley P.,Keenan, Tessa,Chidwick, Harriet,Ledru, Helene,Huonnic, Kler,Huang, Kun,Light, Mark E.,Turner, Nicholas,Jiménez-Barbero, Jesús,Galan, M. Carmen,Fascione, Martin A.,Flitsch, Sabine,Turnbull, W. Bruce,Linclau, Bruno
, p. 6408 - 6411 (2020)
The first synthesis of 3-deoxy-3-fluoro-l-fucose is presented, which employs ad- tol-sugar translation strategy, and involves an enzymatic oxidation of 3-deoxy-3-fluoro-l-fucitol. Enzymatic activation (FKP) and glycosylation using an α-1,2 and an α-1,3 fu
Stereo- and regio-selectivity of diethylaminosulfur trifluoride as a fluorinating reagent for methyl glycosides.
Somawardhana,Brunngraber
, p. 51 - 60 (2007/10/02)
Methyl glycopyranosides reacted with diethylaminosulfur trifluoride (DAST) in the absence of solvent to yield methyl dideoxy-difluoro and deoxy-fluoro glycopyranosides. Methyl alpha-D-glycopyranosides produced 6-deoxy-6-fluoro- and 4,6-dideoxy-4,6-difluor