876126-59-9Relevant articles and documents
Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors
Hu, Rong,Liu, Zhi-Hao,Shi, Yao-Jie,Wang, Ning-Yu,Wang, Wan-Li,Xiao, Kun-Jie,Xu, Ying,Yu, Luo-Ting,Zhu, Yong-Xia,Zuo, Wei-Qiong
, (2020/02/26)
Protein kinase inhibitors and epigenetic regulatory molecules are two main kinds of anticancer drugs developed in recent years. Both kinds of drugs harbor their own advantages and disadvantages in the treatment of cancer, and the development of small mole
Process for the manufacture of dihydropteridinones
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Page/Page column 56-58, (2008/12/07)
Disclosed are processes for preparing dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and in the specification.